Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 16/20 | 0.51 |
| ▸ | CTSL | P07711 | 12/20 | 0.51 |
| ▸ | CTSB | P07858 | 10/20 | 0.51 |
| ▸ | CTSK | P43235 | 7/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5420007 | 0.87 | CTSL (0.54) | CTSSCTSLCTSBCTSK | |
| SCHEMBL6061747 | 0.86 | CTSS (0.49) | CTSSCTSLCTSBCTSKHPGD | |
| SCHEMBL6629257 | 0.86 | CTSS (0.49) | CTSSCTSLCTSBCTSKHPGD | |
| SCHEMBL6742782 | 0.85 | CTSC (0.49) | CTSSCTSLCTSBCTSKHPGD | |
| SCHEMBL6742169 | 0.83 | CTSC (0.47) | CTSSCTSLCTSBCTSKHPGD | |
| SCHEMBL6742769 | 0.83 | CTSC (0.47) | CTSSCTSLCTSBCTSKHPGD | |
| SCHEMBL6061195 | 0.82 | CTSS (0.68) | CTSSCTSLCTSBCTSK | |
| SCHEMBL6742158 | 0.82 | CTSS (0.68) | CTSSCTSLCTSBCTSK | |
| SCHEMBL6738426 | 0.80 | CTSS (0.77) | CTSSCTSLCTSBCTSK | |
| SCHEMBL6738423 | 0.80 | CTSS (0.77) | CTSSCTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383748-A2 | NOVEL COMPOUNDS AND COMPOSITIONS AS CATHEPSIN INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2004-01-28 | — | — | EP | claimed |
| WO-2002051983-A2 | NOVEL COMPOUNDS AND COMPOSITIONS AS CATHEPSIN INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-07-04 | — | — | WO | claimed |