⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28321118 | 0.97 | SLC6A2 (0.46) | — | |
| SCHEMBL23430147 | 0.80 | CYP3A4 (0.38) | — | |
| SCHEMBL27896147 | 0.77 | — | — | |
| SCHEMBL27668974 | 0.77 | — | — | |
| SCHEMBL29153377 | 0.77 | SLC6A2 (0.44) | — | |
| SCHEMBL662302 | 0.75 | PGK1 (0.38) | — | |
| SCHEMBL29361168 | 0.73 | SLC6A2 (0.78) | — | |
| Bromide SCHEMBL9813321 | 0.72 | NOTUM (0.37) | — | |
| SCHEMBL4339266 | 0.71 | SLC6A2 (0.39) | — | |
| SCHEMBL26294543 | 0.71 | CYP3A4 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11780861-B2 | Phosphine reagents for azine fluoroalkylation | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2023-10-10 | — | — | US | disclosed |
| WO-2023171697-A1 | PRODUCTION METHOD FOR FLUORINE-CONTAINING COMPOUND | ＡＧＣ株式会社 | 2023-09-14 | — | — | WO | disclosed |
| US-20230257362-A1 | TRIAZOLONE COMPOUND | MEDSHINE DISCOVERY INC. (CN) | 2023-08-17 | — | — | US | disclosed |
| US-11028105-B2 | Difluoromethyl and difluoromethylene transfer reagents | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2021-06-08 | — | — | US | disclosed |
| CN-109415358-A | 6-aminopyridin-3-ylthiazoles as ROR gamma t modulators | 詹森药业有限公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-109414415-A | The treatment of cutaneous lesions | 皮奎尔治疗公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-105451558-B | Pyrazolyl pyrrolinone and its purposes as herbicide | 先正达参股股份有限公司 | 2018-10-23 | — | — | CN | disclosed |
| CN-108383777-A | The synthetic method of difluoromethyl pyridine derivate | 河南师范大学 | 2018-08-10 | — | — | CN | disclosed |
| CN-108349983-A | The useful glyoxalidine for the treatment of cancer and pyrazinone derivatives | 阿斯利康(瑞典)有限公司 | 2018-07-31 | — | — | CN | disclosed |
| EP-2852584-B1 | SUBSTITUTED DIPYRIDYLAMINES AND USES THEREOF | HOFFMANN LA ROCHE (CH) | 2018-02-28 | — | — | EP | disclosed |
| US-20150080367-A1 | SUBSTITUTED DIPYRIDYLAMINES AND USES THEREOF | GENENTECH, INC. (US) | 2015-03-19 | — | — | US | disclosed |
| CN-104271566-A | Substituted dipyridylamines and uses thereof | HOFFMANN LA ROCHE | 2015-01-07 | — | — | CN | disclosed |
| WO-2013174780-A1 | SUBSTITUTED DIPYRIDYLAMINES AND USES THEREOF | F. HOFFMANN-LA ROCHE AG (CH) | 2013-11-28 | — | — | WO | disclosed |
| US-6737429-B2 | TREATMENT OF HIV MEDIATED DISEASES. | HOFFMANN-LA ROCHE INC. | 2004-05-18 | — | — | US | disclosed |
| EP-1417202-A2 | AMINOPIPERIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | F. HOFFMANN-LA ROCHE AG (CH) | 2004-05-12 | — | — | EP | disclosed |
| EP-1301481-A1 | PYRROLE DERIVATIVES FOR TREATING AIDS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-04-16 | — | — | EP | disclosed |
| US-20030069276-A1 | Amino piperidine derivatives | F.HOFFMANN-LA ROCHE AG (CH) | 2003-04-10 | — | — | US | disclosed |
| WO-2002079186-A2 | AMINOPIPERIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | F. HOFFMANN-LA ROCHE AG (CH) | 2002-10-10 | — | — | WO | disclosed |
| US-20020032221-A1 | Pyrrole derivatives | ROCHE PRODUCTS LIMITED (GB) | 2002-03-14 | — | — | US | disclosed |
| WO-2002002524-A1 | PYRROLE DERIVATIVES FOR TREATING AIDS | F. HOFFMANN-LA ROCHE AG (CH) | 2002-01-10 | — | — | WO | disclosed |