Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6637485 | 0.78 | SMN1; SMN2 (0.55) | NPC1RAB9ASMN1; SMN2LMNAKDM4E | |
| SCHEMBL6631247 | 0.78 | ATR (0.40) | NPC1RAB9ASMN1; SMN2LMNAPOLB | |
| SCHEMBL6629379 | 0.77 | NPC1 (0.46) | CYP2C9NR4A2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6636297 | 0.76 | MEN1 (0.43) | NPC1RAB9ASMN1; SMN2LMNAKDM4E | |
| SCHEMBL6630652 | 0.76 | GAA (0.45) | NPC1RAB9ASMN1; SMN2LMNAKDM4E | |
| SCHEMBL6635964 | 0.76 | SMN1; SMN2 (0.41) | NPC1RAB9ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL6626553 | 0.74 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2POLBMEN1 | |
| SCHEMBL29739476 | 0.69 | ALDH1A1 (0.57) | SMN1; SMN2LMNAKDM4EMEN1KMT2A | |
| SCHEMBL27091696 | 0.68 | TRPV1 (0.59) | CYP2C9NR4A2CNR1TRPV1 | |
| SCHEMBL14082180 | 0.67 | TRPV1 (0.75) | NPC1RAB9ASMN1; SMN2POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458375-A2 | COMPOSITIONS FOR DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003051842-A2 | COMPOSITIONS DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2003-06-26 | — | — | WO | disclosed |