Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | GRM5 | P41594 | 3/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6626553 | 0.83 | NPC1 (0.49) | GAAALDH1A1SMN1; SMN2HTTHSD17B10 | |
| SCHEMBL6635964 | 0.82 | SMN1; SMN2 (0.41) | GAAALDH1A1SMN1; SMN2HTTLMNA | |
| SCHEMBL6636297 | 0.82 | MEN1 (0.43) | GAAALDH1A1SMN1; SMN2HTTLMNA | |
| SCHEMBL6637485 | 0.79 | SMN1; SMN2 (0.55) | GAAALDH1A1SMN1; SMN2HTTLMNA | |
| SCHEMBL6632740 | 0.76 | CYP2C9 (0.46) | SMN1; SMN2LMNAKDM4ERAB9ANPC1 | |
| SCHEMBL6631247 | 0.76 | ATR (0.40) | GAAALDH1A1SMN1; SMN2HTTLMNA | |
| SCHEMBL6633229 | 0.75 | SMN1; SMN2 (0.42) | GAAALDH1A1SMN1; SMN2HTTHSD17B10 | |
| SCHEMBL27406517 | 0.70 | SMN1; SMN2 (0.42) | GAAALDH1A1SMN1; SMN2HTTLMNA | |
| SCHEMBL6634859 | 0.70 | RAB9A (0.41) | GAAALDH1A1SMN1; SMN2HTTHSD17B10 | |
| SCHEMBL6631787 | 0.69 | KMT2A (0.42) | GAAALDH1A1SMN1; SMN2HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458375-A2 | COMPOSITIONS FOR DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003051842-A2 | COMPOSITIONS DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2003-06-26 | — | — | WO | disclosed |