SCHEMBL6632742

SCHEMBL6632742

CC(=O)NCC1Cc2cccc3cccc1c23

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 18/20 1.00
MTNR1B P49286 18/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6635575 0.86 MTNR1A (1.00) MTNR1AMTNR1B
SCHEMBL6633601 0.86 MTNR1A (1.00) MTNR1AMTNR1B
SCHEMBL6635720 0.84 MTNR1B (1.00) MTNR1AMTNR1B
SCHEMBL6632914 0.83 MTNR1A (1.00) MTNR1AMTNR1B
SCHEMBL6633104 0.82 MTNR1A (0.70) MTNR1AMTNR1B
SCHEMBL6634661 0.79 MTNR1A (0.65) MTNR1AMTNR1B
SCHEMBL6633694 0.78 MTNR1B (1.00) MTNR1AMTNR1B
SCHEMBL6633198 0.78 MTNR1A (0.64) MTNR1AMTNR1B
SCHEMBL4590905 0.77 MTNR1A (0.63) MTNR1AMTNR1B
SCHEMBL6634999 0.76 MTNR1A (0.61) MTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1247528-C Novel tricyclic compounds, preparation method and pharmaceutical compositions containing same SIRVIR LAB (FR) 2006-03-29 CN claimed
EP-1047664-B1 NOVEL TRICYCLIC COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME SERVIER LAB (FR) 2004-05-19 EP claimed
US-6423870-B1 ANTICOAGULANTS; CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS LES LABORATOIRES SERVIER (FR) 2002-07-23 US claimed
CN-1285817-A Novel tricyclic compounds, preparation method and pharmaceutical compositions containing same ADIR (FR) 2001-02-28 CN claimed
CN-1247528-C Novel tricyclic compounds, preparation method and pharmaceutical compositions containing same SIRVIR LAB (FR) 2006-03-29 CN disclosed
EP-1047664-B1 NOVEL TRICYCLIC COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME SERVIER LAB (FR) 2004-05-19 EP disclosed
US-6423870-B1 ANTICOAGULANTS; CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS LES LABORATOIRES SERVIER (FR) 2002-07-23 US disclosed
CN-1285817-A Novel tricyclic compounds, preparation method and pharmaceutical compositions containing same ADIR (FR) 2001-02-28 CN disclosed
EP-1047664-A1 NOVEL TRICYCLIC COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME ADIR ET COMPAGNIE (FR) 2000-11-02 EP disclosed
WO-1999036392-A1 NOVEL TRICYCLIC COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME ADIR ET COMPAGNIE (FR) 1999-07-22 WO disclosed