SCHEMBL663296

SCHEMBL663296

CCCC/C=C1\CC(C)OC1=O

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 6/20 0.44
PPARG P37231 6/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
DYRK1A Q13627 2/20 0.41
DYRK1B Q9Y463 2/20 0.41
CLK1 P49759 1/20 0.41
CCR6 P51684 1/20 0.40
MAOA P21397 1/20 0.38
PIK3CA P42336 1/20 0.36
DYRK2 Q92630 1/20 0.36
KDM4E B2RXH2 1/20 0.36
RAB9A P51151 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21895492 1.00 PRKCA (0.44) PRKCAPPARGSMN1; SMN2DYRK1ADYRK1B
SCHEMBL5936319 1.00 PRKCA (0.44) PRKCAPPARGSMN1; SMN2DYRK1ADYRK1B
SCHEMBL5936330 0.95 PRKCA (0.49) PRKCAPPARGSMN1; SMN2DYRK1ADYRK1B
SCHEMBL5936344 0.95 PRKCA (0.49) PRKCAPPARGSMN1; SMN2DYRK1ADYRK1B
SCHEMBL5936317 0.95 PRKCA (0.49) PRKCAPPARGSMN1; SMN2DYRK1ADYRK1B
SCHEMBL664887 0.95 PRKCA (0.49) PRKCAPPARGSMN1; SMN2DYRK1ADYRK1B
SCHEMBL666234 0.93 PRKCA (0.51) PRKCAPPARG
SCHEMBL10186552 0.93 PRKCA (0.51) PRKCAPPARG
SCHEMBL9254632 0.93 PRKCA (0.51) PRKCAPPARG
SCHEMBL21182172 0.93 PRKCA (0.51) PRKCAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4074807-B1 COMPOSITIONS COMPRISING A FLUOROOLEFIN CHEMOURS CO FC LLC (US) 2025-07-09 EP disclosed
EP-3543310-B2 COMPOSITIONS COMPRISING HFC-1234YF AND HFC-32 CHEMOURS CO FC LLC (US) 2024-07-03 EP disclosed
EP-3299435-B1 METHOD OF PREPARING A COMPOSITION COMPRISING HFC-1234YF CHEMOURS CO FC LLC (US) 2024-06-26 EP disclosed
EP-2749623-B2 Method for replacing a high GWP refrigerant in a refrigeration, air-conditioning, or heat pump apparatus CHEMOURS CO FC LLC (US) 2024-02-21 EP disclosed
EP-3309233-B2 COMPOSITIONS COMPRISING HFC-1234YF AND HFC-152A CHEMOURS CO FC LLC (US) 2024-02-21 EP disclosed
US-20230265330-A1 COMPOSITIONS COMPRISING A FLUOROOLEFIN THE CHEMOURS COMPANY FC, LLC (US) 2023-08-24 US disclosed
US-11674067-B2 Compositions comprising a fluoroolefin THE CHEMOURS COMPANY FC, LLC (US) 2023-06-13 US disclosed
US-20220389297-A1 COMPOSITIONS COMPRISING A FLUOROOLEFIN THE CHEMOURS COMPANY FC, LLC (US) 2022-12-08 US disclosed
US-20220389298-A1 COMPOSITIONS COMPRISING A FLUOROOLEFIN THE CHEMOURS COMPANY FC, LLC (US) 2022-12-08 US disclosed
EP-4074807-A1 COMPOSITIONS COMPRISING A FLUOROOLEFIN The Chemours Company FC, LLC (US) 2022-10-19 EP disclosed
US-20050156139-A1 1-Ethoxy-1,1,2,2,3,3,4,4,4,-nonafluorobutane refrigerant compositions comprising a fluoroether and uses thereof E. I. DU PONT DE NEMOURS AND COMPANY 2005-07-21 US disclosed
US-20050151113-A1 Hydrofluorocarbon refrigerant compositions and uses thereof E. I. DU PONT DE NEMOURS AND COMPANY 2005-07-14 US disclosed
US-20050151110-A1 Fluoroether refrigerant compositions and uses thereof E. I. DU PONT DE NEMOURS AND COMPANY 2005-07-14 US disclosed
US-20050151112-A1 1,1,1,2,2,3,3,4,4-Nonafluoro-4-methoxybutane refrigerant compositions comprising hydrofluorocarbon, and uses thereof E. I. DU PONT DE NEMOURS AND COMPANY 2005-07-14 US disclosed
US-20050151111-A1 1,1,1,3,3-Pentafluorobutane refrigerant or heat transfer fluid compositions comprising hydrofluorocarbon and uses thereof E. I. DU PONT DE NEMOURS AND COMPANY 2005-07-14 US disclosed
US-20050145822-A1 Refrigerant compositions comprising UV fluorescent dye and solubilizing agent E. I. DU PONT DE NEMOURS AND COMPANY 2005-07-07 US disclosed
US-20050127321-A1 Compositions containing lactone compatibilizers E. I. DU PONT DE NEMOURS AND COMPANY 2005-06-16 US disclosed
US-20050109978-A1 Refrigerant compositions comprising performance enhancing additives LECK THOMAS J (US) 2005-05-26 US disclosed
WO-2005014565-A2 CIS-3,5-DISUBSTITUTED-DIHYDRO-FURAN-2-ONES AND THE PREPARATION AND USE THEREOF E.I. DUPONT DE NEMOURS AND COMPANY (US) 2005-02-17 WO disclosed
US-6841088-B2 Fluorocarbon, oxygenated and non-oxygenated lubricant, and compatibilizer composition, and method for replacing refrigeration composition in a refrigeration system E. I. DU PONT DE NEMOURS AND COMPANY (US) 2005-01-11 US disclosed