SCHEMBL6632987

SCHEMBL6632987

CCC(=O)NCC1Cc2cccc3ccc(OC)c1c23

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MTNR1B P49286 16/20 1.00
MTNR1A P48039 15/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6634224 0.91 MTNR1B (1.00) MTNR1BMTNR1A
SCHEMBL6633736 0.89 MTNR1B (1.00) MTNR1BMTNR1A
SCHEMBL6633694 0.88 MTNR1B (1.00) MTNR1BMTNR1A
SCHEMBL6632767 0.88 MTNR1B (1.00) MTNR1BMTNR1A
SCHEMBL6633517 0.81 MTNR1B (1.00) MTNR1BMTNR1A
SCHEMBL6632967 0.81 MTNR1B (1.00) MTNR1BMTNR1A
SCHEMBL6634692 0.80 MTNR1B (1.00) MTNR1BMTNR1A
SCHEMBL6633601 0.79 MTNR1A (1.00) MTNR1BMTNR1A
SCHEMBL6632992 0.79 MTNR1B (1.00) MTNR1BMTNR1A
SCHEMBL6632868 0.78 MTNR1B (1.00) MTNR1BMTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1047664-B1 NOVEL TRICYCLIC COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME SERVIER LAB (FR) 2004-05-19 EP claimed
US-6423870-B1 ANTICOAGULANTS; CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS LES LABORATOIRES SERVIER (FR) 2002-07-23 US claimed
EP-1047664-A1 NOVEL TRICYCLIC COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME ADIR ET COMPAGNIE (FR) 2000-11-02 EP claimed
WO-1999036392-A1 NOVEL TRICYCLIC COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME ADIR ET COMPAGNIE (FR) 1999-07-22 WO claimed
EP-1047664-B1 NOVEL TRICYCLIC COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME SERVIER LAB (FR) 2004-05-19 EP disclosed
US-6423870-B1 ANTICOAGULANTS; CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS LES LABORATOIRES SERVIER (FR) 2002-07-23 US disclosed
EP-1047664-A1 NOVEL TRICYCLIC COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME ADIR ET COMPAGNIE (FR) 2000-11-02 EP disclosed
WO-1999036392-A1 NOVEL TRICYCLIC COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME ADIR ET COMPAGNIE (FR) 1999-07-22 WO disclosed