Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 8/20 | 0.58 |
| ▸ | FNTB | P49356 | 8/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.44 |
| ▸ | HSD17B3 | P37058 | 4/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | BRS3 | P32247 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6635023 | 0.93 | FNTA (0.49) | FNTAFNTBABCB1HSD17B3BRD4 | |
| SCHEMBL6633140 | 0.85 | FNTA (0.47) | FNTAFNTBABCB1HSD17B3BRD4 | |
| SCHEMBL6635731 | 0.85 | FNTA (0.56) | FNTAFNTBBRD4CA1CA2 | |
| SCHEMBL6616410 | 0.76 | CYP11B2 (0.52) | FNTAFNTBBRD4 | |
| SCHEMBL3501703 | 0.73 | FNTA (0.71) | FNTAFNTBABCB1BRD4BRS3 | |
| SCHEMBL6632636 | 0.73 | FNTA (0.56) | FNTAFNTBABCB1HSD17B3BRD4 | |
| SCHEMBL6615352 | 0.70 | FNTA (0.62) | FNTAFNTBCA1CA2CA4 | |
| SCHEMBL6637047 | 0.70 | FNTA (0.57) | FNTAFNTBBRD4CA1CA2 | |
| SCHEMBL6637054 | 0.70 | FNTA (0.57) | FNTAFNTBBRD4CA1CA2 | |
| SCHEMBL3500100 | 0.67 | FNTA (0.73) | FNTAFNTBHSD17B3BRD4BRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481975-A1 | Inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-12-01 | — | — | EP | disclosed |
| US-6455523-B1 | ADMINISTERING 1,4-BENZODIAZEPINE DERIVATIVE AS ANTITUMOR OR ANTICARCINOGENIC AGENT | BRISTOL-MYERS SQUIBB COMPANY | 2002-09-24 | — | — | US | disclosed |
| US-6011029-A | BENZODIAZEPINE COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-01-04 | — | — | US | disclosed |