Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9328485 | 0.82 | AOC3 (0.52) | AOC3ARNPC1RAB9AKDM4E | |
| SCHEMBL30990546 | 0.82 | AOC3 (0.52) | AOC3ARNPC1RAB9AKDM4E | |
| SCHEMBL10613155 | 0.82 | AOC3 (0.52) | AOC3ARNPC1RAB9AKDM4E | |
| SCHEMBL18427579 | 0.80 | AOC3 (0.50) | AOC3ARNPC1RAB9AKDM4E | |
| SCHEMBL30637653 | 0.78 | AOC3 (0.48) | AOC3ARNPC1RAB9AKDM4E | |
| SCHEMBL29258496 | 0.78 | AOC3 (0.48) | AOC3ARNPC1RAB9AKDM4E | |
| SCHEMBL8427260 | 0.78 | AOC3 (0.48) | AOC3ARNPC1RAB9AKDM4E | |
| SCHEMBL10532274 | 0.78 | AR (0.55) | AOC3ARNPC1RAB9AKDM4E | |
| SCHEMBL6824543 | 0.75 | AR (0.49) | AOC3ARNPC1RAB9AKDM4E | |
| Biphenyl SCHEMBL9470119 | 0.75 | NPC1 (0.57) | AOC3ARNPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040133014-A1 | 3-Sulfenylation of indole-2-carboxylates | WALL HAMILTON HARRIET (US) | 2004-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040133014-A1 | 3-Sulfenylation of indole-2-carboxylates | TST, IDO2, INMT | AOC3 334/4885AR 3310/4885NPC1 4452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.