Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 3/20 | 0.52 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.48 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.48 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6631919 | 0.90 | ITGA4 (0.52) | ITGA4ITGB1ITGB7ITGA5GAA | |
| SCHEMBL3855551 | 0.89 | ITGA4 (0.54) | ITGA4ITGB1ITGB7ITGA5KMT2A | |
| SCHEMBL3851005 | 0.88 | ITGA4 (0.53) | ITGA4ITGB1ITGB7ITGA5KMT2A | |
| SCHEMBL3859212 | 0.86 | ITGA4 (0.53) | ITGA4ITGB1ITGB7ITGA5KMT2A | |
| SCHEMBL5175369 | 0.86 | ITGA4 (0.51) | ITGA4ITGB1ITGB7ITGA5KMT2A | |
| SCHEMBL7066750 | 0.86 | FKBP1A (0.58) | ITGA4ITGB1ITGA5GAAHPGD | |
| SCHEMBL6708385 | 0.85 | KMT2A (0.56) | ITGA4ITGB1ITGA5KMT2AALDH1A1 | |
| SCHEMBL3849111 | 0.85 | ITGA4 (0.51) | ITGA4ITGB1ITGB7ITGA5KMT2A | |
| SCHEMBL3853413 | 0.85 | ITGA4 (0.51) | ITGA4ITGB1ITGB7ITGA5KMT2A | |
| SCHEMBL3850548 | 0.85 | ITGA4 (0.50) | ITGA4ITGB1ITGB7ITGA5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000051-B1 | CARBAMYLOXY COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARM INC (US) | 2004-05-19 | — | — | EP | claimed |