Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18133680 | 0.84 | RAB9A (0.39) | SMN1; SMN2RAB9AALDH1A1KMT2AHPGD | |
| SCHEMBL6635952 | 0.84 | RAB9A (0.39) | SMN1; SMN2RAB9AALDH1A1KMT2AHPGD | |
| SCHEMBL1563254 | 0.77 | RAB9A (0.40) | SMN1; SMN2RAB9AALDH1A1KMT2A | |
| SCHEMBL17666907 | 0.70 | ALDH1A1 (0.50) | ALDH1A1HPGD | |
| SCHEMBL18680191 | 0.70 | KDM4E (0.43) | SMN1; SMN2RAB9AALDH1A1MAPT | |
| SCHEMBL1562182 | 0.70 | ALDH1A1 (0.37) | SMN1; SMN2RAB9AALDH1A1MAPTTDP1 | |
| SCHEMBL1562184 | 0.70 | ALDH1A1 (0.37) | SMN1; SMN2RAB9AALDH1A1MAPTTDP1 | |
| SCHEMBL17666908 | 0.70 | ALDH1A1 (0.50) | ALDH1A1HPGD | |
| SCHEMBL6638403 | 0.70 | ALDH1A1 (0.37) | SMN1; SMN2RAB9AALDH1A1MAPTTDP1 | |
| SCHEMBL27905423 | 0.68 | ALDH1A1 (0.35) | SMN1; SMN2RAB9AALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0909788-B1 | RUBBER COMPOSITION AND PNEUMATIC TIRES | BRIDGESTONE CORP (JP) | 2004-12-01 | — | — | EP | disclosed |
| EP-1420044-A2 | Rubber composition and pneumatic tire | Bridgestone Corporation (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-6380288-B1 | LOW HEAT GENERATION PROPERTY, AGING REISTANCE, ALSO FOR PRODUCING VIBRATION ISOLATORS, BELTS AND HOSES AS WELL AS TIRE MATERIALS SUCH AS TIRE TREADS, UNDERTREADS, CARCASSES, SIDE WALLS AND BEADS | BRIDGESTONE CORPORATION | 2002-04-30 | — | — | US | disclosed |
| EP-0909788-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRES | Bridgestone Corporation (JP) | 1999-04-21 | — | — | EP | disclosed |