Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 18/20 | 0.60 |
| ▸ | DAGLA | Q9Y4D2 | 13/20 | 0.53 |
| ▸ | CES1 | P23141 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5422144 | 0.81 | FAAH (0.59) | FAAHDAGLACES1 | |
| SCHEMBL3963517 | 0.76 | FAAH (0.62) | FAAHDAGLACES1 | |
| SCHEMBL5420107 | 0.73 | FAAH (0.56) | FAAHDAGLACES1 | |
| SCHEMBL3961770 | 0.71 | FAAH (1.00) | FAAHDAGLACES1 | |
| SCHEMBL7261197 | 0.71 | SORD (0.43) | FAAHDAGLA | |
| SCHEMBL3963662 | 0.70 | FAAH (1.00) | FAAHDAGLACES1 | |
| SCHEMBL11643069 | 0.70 | DAGLA (0.60) | FAAHDAGLACES1 | |
| SCHEMBL3961999 | 0.69 | FAAH (1.00) | FAAHDAGLACES1 | |
| SCHEMBL3968868 | 0.69 | FAAH (1.00) | FAAHDAGLACES1 | |
| SCHEMBL3964457 | 0.69 | FAAH (1.00) | FAAHDAGLACES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383748-A2 | NOVEL COMPOUNDS AND COMPOSITIONS AS CATHEPSIN INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002051983-A2 | NOVEL COMPOUNDS AND COMPOSITIONS AS CATHEPSIN INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-07-04 | — | — | WO | disclosed |