Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 3/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.35 |
| ▸ | CKS1B | P61024 | 1/20 | 0.34 |
| ▸ | SKP1 | P63208 | 1/20 | 0.34 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.32 |
| ▸ | CDK2 | P24941 | 2/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.31 |
| ▸ | STK17B | O94768 | 1/20 | 0.31 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7852849 | 0.91 | CDK5 (0.41) | CDK5CDK5R1CKS1BSKP1SKP2 | |
| SCHEMBL6046933 | 0.84 | KDM4E (0.39) | CKS1BSKP1SKP2BRD4 | |
| SCHEMBL7852502 | 0.79 | CDK5 (0.36) | CDK5CDK5R1FGFR1FGFR4BRD4 | |
| SCHEMBL13037052 | 0.79 | TLR7 (0.36) | CKS1BSKP1SKP2CCNE2CCNE1 | |
| SCHEMBL10077177 | 0.79 | CCNE1 (0.40) | CKS1BSKP1SKP2CCNE2CCNE1 | |
| SCHEMBL20633993 | 0.78 | CCNE2 (0.35) | CKS1BSKP1SKP2CCNE2CCNE1 | |
| SCHEMBL7843680 | 0.77 | CCNE2 (0.39) | CKS1BSKP1SKP2CCNE2CCNE1 | |
| SCHEMBL6635297 | 0.77 | FGFR1 (0.48) | CDK5CDK5R1FGFR1FGFR4 | |
| SCHEMBL430142 | 0.77 | CDK2 (0.36) | CKS1BSKP1SKP2BRD4CCNE2 | |
| SCHEMBL432421 | 0.77 | CKS1B (0.36) | CKS1BSKP1SKP2BRD4CCNE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1085020-B1 | Synthesis of peptide nucleic acids | PNA DIAGNOSTICS APS APPLIED BI (DK) | 2004-03-17 | — | — | EP | disclosed |
| EP-1085020-A1 | Synthesis of modified diaminopurines and their incorporation into oligomers | DAKO A/S (DK) | 2001-03-21 | — | — | EP | disclosed |