SCHEMBL6046933

SCHEMBL6046933

CC(C)C(=O)Nc1nc2c(ncn2CC(=O)N(CCNC(=O)OC(C)(C)C)CC(=O)O)c(=O)[nH]1

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.38
TSHR P16473 1/20 0.38
KMT2A Q03164 1/20 0.38
HPRT1 P00492 1/20 0.35
CKS1B P61024 1/20 0.34
SKP1 P63208 1/20 0.34
SKP2 Q13309 1/20 0.34
BRD4 O60885 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7263683 0.89 L3MBTL1 (0.36) MEN1TSHRKMT2ACKS1BSKP1
SCHEMBL458786 0.86 MEN1 (0.38) MEN1TSHRKMT2ACKS1BSKP1
SCHEMBL10078205 0.86 HPRT1 (0.49) MEN1TSHRKMT2AHPRT1
SCHEMBL7852849 0.84 CDK5 (0.41) CKS1BSKP1SKP2BRD4
SCHEMBL6635546 0.84 CDK5 (0.35) CKS1BSKP1SKP2BRD4
SCHEMBL432421 0.81 CKS1B (0.36) HPRT1CKS1BSKP1SKP2BRD4
SCHEMBL13037053 0.80 CKS1B (0.35) HPRT1CKS1BSKP1SKP2
SCHEMBL13660691 0.79 HPRT1 (0.41) MEN1TSHRKMT2AHPRT1
SCHEMBL10077177 0.78 CCNE1 (0.40) HPRT1CKS1BSKP1SKP2
SCHEMBL15617403 0.78 KMT2A (0.42) KMT2ABRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1105525-B1 A PROCESS FOR PREPARING PEPTIDE NUCLEIC ACID PROBE USING POLYMERIC PHOTOACID GENERATOR SAMSUNG ELECTRONICS CO LTD (KR) 2006-11-02 EP disclosed
US-6660479-B2 Derivatizing surface of a solid matrix and attaching linker with acid- labile protecting group on solid matrix; coating solid matrix with polymeric photoacid generator(PAG); exposing solid matrix thus coated to light to generate acid; reacting SAMSUNG ELECTRONICS CO., LTD. (KR) 2003-12-09 US disclosed
US-20020122874-A1 Process for preparing peptide nucleic acid probe using polymeric photoacid generator SAMSUNG ELECTRONICS CO., LTD. (KR) 2002-09-05 US disclosed
US-6359125-B1 DERIVATIZING SURFACE OF SOLID MATRIX WITH AMINOALKYLOXYSILANE AND ATTACHING LINKER WITH ACID-LABILE PROTECTING GROUP TO AMINE GROUP ON MATRIX, COATING MATRIX WITH POLYMERIC PHOTOACID GENERATOR, EXPOSING TO LIGHT, ATTACHING PEPTIDE NUCLEIC ACID SAMSUNG ELECTRONICS CO., LTD. (KR) 2002-03-19 US disclosed