Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 10/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10058977 | 0.94 | GAA (0.69) | HDAC1HDAC3HDAC2POLBGAA | |
| SCHEMBL6637896 | 0.89 | HDAC3 (0.67) | HDAC1HDAC3HDAC2POLBNPC1 | |
| SCHEMBL28929263 | 0.86 | NPC1 (0.62) | HDAC1HDAC3HDAC2POLBLMNA | |
| SCHEMBL9205365 | 0.85 | THRA (0.59) | HDAC1POLBGAALMNAALDH1A1 | |
| SCHEMBL10058954 | 0.84 | GAA (0.85) | HDAC1HDAC3HDAC2POLBGAA | |
| SCHEMBL9202138 | 0.84 | GAA (0.56) | HDAC1HDAC3HDAC2POLBGAA | |
| SCHEMBL14491137 | 0.83 | KMT2A (0.67) | HDAC1HDAC3HDAC2POLBNPC1 | |
| SCHEMBL6637333 | 0.83 | POLB (0.81) | POLBGAALMNAALDH1A1MEN1 | |
| SCHEMBL6637069 | 0.82 | HDAC3 (0.89) | HDAC1HDAC3HDAC2HDAC8HDAC4 | |
| SCHEMBL15482048 | 0.80 | MEN1 (0.61) | HDAC1HDAC3HDAC2POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1420044-A2 | Rubber composition and pneumatic tire | Bridgestone Corporation (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-6380288-B1 | LOW HEAT GENERATION PROPERTY, AGING REISTANCE, ALSO FOR PRODUCING VIBRATION ISOLATORS, BELTS AND HOSES AS WELL AS TIRE MATERIALS SUCH AS TIRE TREADS, UNDERTREADS, CARCASSES, SIDE WALLS AND BEADS | BRIDGESTONE CORPORATION | 2002-04-30 | — | — | US | disclosed |
| EP-0909788-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRES | Bridgestone Corporation (JP) | 1999-04-21 | — | — | EP | disclosed |