Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 17/20 | 0.89 |
| ▸ | HDAC2 | Q92769 | 14/20 | 0.89 |
| ▸ | HDAC1 | Q13547 | 13/20 | 0.89 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.58 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6638846 | 0.94 | HDAC3 (1.00) | HDAC3HDAC2HDAC1HDAC11HDAC8 | |
| SCHEMBL17141739 | 0.88 | HDAC3 (1.00) | HDAC3HDAC2HDAC1HDAC8NCOR2 | |
| SCHEMBL3247728 | 0.86 | HDAC1 (0.74) | HDAC3HDAC2HDAC1HDAC11HDAC8 | |
| SCHEMBL10600882 | 0.86 | HDAC1 (0.74) | HDAC3HDAC2HDAC1HDAC11HDAC8 | |
| SCHEMBL9099931 | 0.86 | HDAC1 (0.74) | HDAC3HDAC2HDAC1HDAC11HDAC8 | |
| SCHEMBL28444240 | 0.86 | HDAC1 (0.74) | HDAC3HDAC2HDAC1HDAC11HDAC8 | |
| SCHEMBL11220445 | 0.86 | HDAC1 (0.74) | HDAC3HDAC2HDAC1HDAC11HDAC8 | |
| SCHEMBL6635555 | 0.82 | HDAC1 (0.65) | HDAC3HDAC2HDAC1HDAC11HDAC8 | |
| SCHEMBL6640133 | 0.82 | HDAC3 (0.77) | HDAC3HDAC2HDAC1HDAC11HDAC8 | |
| SCHEMBL6638062 | 0.82 | HDAC3 (0.77) | HDAC3HDAC2HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1420044-A2 | Rubber composition and pneumatic tire | Bridgestone Corporation (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-6380288-B1 | LOW HEAT GENERATION PROPERTY, AGING REISTANCE, ALSO FOR PRODUCING VIBRATION ISOLATORS, BELTS AND HOSES AS WELL AS TIRE MATERIALS SUCH AS TIRE TREADS, UNDERTREADS, CARCASSES, SIDE WALLS AND BEADS | BRIDGESTONE CORPORATION | 2002-04-30 | — | — | US | disclosed |
| EP-0909788-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRES | Bridgestone Corporation (JP) | 1999-04-21 | — | — | EP | disclosed |