Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 19/20 | 1.00 |
| ▸ | MTNR1A | P48039 | 18/20 | 1.00 |
| ▸ | NQO2 | P16083 | 1/20 | 0.64 |
| ▸ | HTR2C | P28335 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6633692 | 0.89 | MTNR1B (1.00) | MTNR1BMTNR1AHTR2C | |
| SCHEMBL6634692 | 0.89 | MTNR1B (1.00) | MTNR1BMTNR1A | |
| SCHEMBL6637527 | 0.88 | MTNR1A (1.00) | MTNR1BMTNR1ANQO2HTR2C | |
| SCHEMBL6634273 | 0.88 | MTNR1B (0.81) | MTNR1BMTNR1A | |
| SCHEMBL6634192 | 0.83 | MTNR1A (0.87) | MTNR1BMTNR1ANQO2HTR2C | |
| SCHEMBL6633599 | 0.83 | MTNR1A (1.00) | MTNR1BMTNR1ANQO2 | |
| SCHEMBL6640384 | 0.81 | MTNR1A (0.87) | MTNR1BMTNR1ANQO2HTR2C | |
| SCHEMBL7743388 | 0.81 | MTNR1B (0.70) | MTNR1BMTNR1A | |
| SCHEMBL6636372 | 0.80 | MTNR1B (0.66) | MTNR1BMTNR1A | |
| SCHEMBL6633694 | 0.80 | MTNR1B (1.00) | MTNR1BMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047664-B1 | NOVEL TRICYCLIC COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2004-05-19 | — | — | EP | claimed |
| US-6423870-B1 | ANTICOAGULANTS; CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS | LES LABORATOIRES SERVIER (FR) | 2002-07-23 | — | — | US | claimed |
| EP-1047664-B1 | NOVEL TRICYCLIC COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2004-05-19 | — | — | EP | disclosed |
| US-6423870-B1 | ANTICOAGULANTS; CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS | LES LABORATOIRES SERVIER (FR) | 2002-07-23 | — | — | US | disclosed |