SCHEMBL6635671

SCHEMBL6635671

CCN(CC)c1ccc(C(=O)C(=O)c2ccccc2)c(O)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.64
KMT2A Q03164 4/20 0.64
SMN1; SMN2 Q16637 3/20 0.64
L3MBTL1 Q9Y468 3/20 0.64
MAPT P10636 6/20 0.49
ALDH1A1 P00352 5/20 0.49
KDM4E B2RXH2 3/20 0.49
GAA P10253 3/20 0.49
LMNA P02545 2/20 0.49
POLB P06746 1/20 0.49
MAOB P27338 1/20 0.47
RAB9A P51151 4/20 0.46
MAPK1 P28482 1/20 0.46
HTT P42858 1/20 0.46
CNR2 P34972 1/20 0.45
NPC1 O15118 3/20 0.44
NOX1 Q9Y5S8 1/20 0.44
HPGD P15428 1/20 0.44
ALOX12 P18054 1/20 0.44
CYP3A4 P08684 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2780893 0.87 MEN1 (0.74) MEN1KMT2ASMN1; SMN2L3MBTL1MAPT
SCHEMBL29437222 0.87 MEN1 (0.74) MEN1KMT2ASMN1; SMN2L3MBTL1MAPT
SCHEMBL2016398 0.82 MEN1 (0.60) MEN1KMT2ASMN1; SMN2L3MBTL1MAPT
SCHEMBL503775 0.81 MEN1 (0.75) MEN1KMT2ASMN1; SMN2L3MBTL1MAPT
SCHEMBL14982110 0.81 RAB9A (0.63) MEN1KMT2AL3MBTL1MAPTALDH1A1
SCHEMBL4938394 0.80 MEN1 (0.55) MEN1KMT2ASMN1; SMN2L3MBTL1MAPT
SCHEMBL27913467 0.80 MEN1 (0.89) MEN1KMT2ASMN1; SMN2L3MBTL1MAPT
Benzil SCHEMBL28412929 0.80 RAB9A (0.50) MEN1KMT2ASMN1; SMN2L3MBTL1MAPT
SCHEMBL22939653 0.79 MEN1 (0.77) MEN1KMT2ASMN1; SMN2L3MBTL1MAPT
SCHEMBL27826035 0.79 MEN1 (0.67) MEN1KMT2ASMN1; SMN2L3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1466585-A2 Use of of aminosubstituted hydroxybenzophenones as photostable UV-filter in cosmetic and pharmaceutical preparations BASF AKTIENGESELLSCHAFT (DE) 2004-10-13 EP disclosed
EP-1046391-B1 Use of aminosubstituted hydroxybenzophenones as photostable UV-filters in cosmetic and pharmaceutical preparations BASF AG (DE) 2004-09-15 EP disclosed
US-6409995-B1 SUNSCREEN BASF AKTIENGESELLSCHAFT (DE) 2002-06-25 US disclosed
EP-1046391-A2 Use of aminosubstituted hydroxybenzophenones as photostable UV-filters in cosmetic and pharmaceutical preparations BASF AKTIENGESELLSCHAFT (DE) 2000-10-25 EP disclosed