SCHEMBL2780893

SCHEMBL2780893

CCN(CC)c1ccc(C(=O)c2ccccc2)c(O)c1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.74
KMT2A Q03164 5/20 0.74
SMN1; SMN2 Q16637 2/20 0.74
L3MBTL1 Q9Y468 1/20 0.74
MAOB P27338 1/20 0.57
GAA P10253 4/20 0.57
USP2 O75604 1/20 0.57
KEAP1 Q14145 1/20 0.57
NFE2L2 Q16236 1/20 0.57
ALDH1A1 P00352 6/20 0.56
KDM4E B2RXH2 4/20 0.56
POLB P06746 1/20 0.56
HPGD P15428 6/20 0.54
LMNA P02545 3/20 0.54
MAPK1 P28482 2/20 0.54
HTT P42858 2/20 0.54
CYP1A2 P05177 1/20 0.54
PGR P06401 1/20 0.54
CYP2D6 P10635 1/20 0.54
SLC6A2 P23975 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29437222 1.00 MEN1 (0.74) MEN1KMT2ASMN1; SMN2L3MBTL1MAOB
SCHEMBL29152906 0.90 MEN1 (0.69) MEN1KMT2ASMN1; SMN2L3MBTL1MAOB
SCHEMBL4654342 0.90 MEN1 (0.65) MEN1KMT2ASMN1; SMN2L3MBTL1MAOB
SCHEMBL27826035 0.89 MEN1 (0.67) MEN1KMT2ASMN1; SMN2L3MBTL1MAOB
SCHEMBL27913467 0.88 MEN1 (0.89) MEN1KMT2ASMN1; SMN2L3MBTL1MAOB
SCHEMBL22939653 0.87 MEN1 (0.77) MEN1KMT2ASMN1; SMN2L3MBTL1MAOB
SCHEMBL19143312 0.87 MEN1 (0.57) MEN1KMT2ASMN1; SMN2L3MBTL1MAOB
SCHEMBL6635671 0.87 MEN1 (0.64) MEN1KMT2ASMN1; SMN2L3MBTL1MAOB
SCHEMBL22938967 0.86 MEN1 (0.81) MEN1KMT2ASMN1; SMN2L3MBTL1MAOB
SCHEMBL29226741 0.86 ALDH1A1 (0.77) MEN1KMT2ASMN1; SMN2L3MBTL1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117903102-A Fluorescent probe and preparation method and application thereof 曲阜师范大学 2024-04-19 CN claimed
EP-1323413-B1 Light screening composition comprising a 1,3,5-triazine derivative, a dibenzoylmethane derivative and an amino substituted 2-hydroxybenzophenone derivative L'ORÉAL (FR) 2016-12-21 EP claimed
US-6703002-B2 Synergistically UV-photoprotecting sunscreen compositions comprising camphorsulfonic acid/benzophenone compounds Societe L′Oreal S.A. (FR) 2004-03-09 US claimed
US-6699460-B2 UV-photostabilized sunscreen compositions comprising dibenzoylmethane/triazine/benzophenone compounds SOCIETE L'OREAL S.A. (FR) 2004-03-02 US claimed
US-6699461-B2 UV-photostabilized sunscreen compositions comprising dibenzoylmethane/benzophenone compounds SOCIETE L'OREAL S.A. (FR) 2004-03-02 US claimed
US-6635239-B2 Topically applicable cosmetic/dermatological self-tanning composition with colorations that are more chromatic, are more stable over time, and have good homogeneity SOCIETE L'OREAL S.A. (FR) 2003-10-21 US claimed
US-6627180-B2 Particles having protection factor UV-APPD and an amino substituted 2-hydroxybenzophenone SOCIETE L'OREAL S.A. (FR) 2003-09-30 US claimed
US-6627179-B2 Benzotriazole substituted silicon compound or polymer, dibenzoylmethane derivative and an amino-substituted 2-hydroxybenzophenone SOCIETE L'OREAL S.A. (FR) 2003-09-30 US claimed
US-20030180230-A1 UV-photostabilized sunscreen compositions comprising dibenzoylmethane/triazine/benzophenone compounds SOCIETE L'OREAL S.A. (FR) 2003-09-25 US claimed
US-20030161794-A1 Synergistically UV-photoprotecting sunscreen compositions comprising camphorsulfonic acid/benzophenone compounds SOCIETE L'OREAL S.A. (FR) 2003-08-28 US claimed
US-20030161793-A1 UV-photostabilized sunscreen compositions comprising dibenzoylmethane/benzophenone compounds SOCIETE L'OREAL S.A. (FR) 2003-08-28 US claimed
US-20030157038-A1 SYNERGISTICALLY UV-PHOTOPROTECTING MIXED SUNSCREEN COMPOSITIONS SOCIETE L'OREAL S.A. (FR) 2003-08-21 US claimed
US-20030152532-A1 SYNERGISTICALLY UV-PHOTOPROTECTING COMPOSITIONS COMPRISING MIXED SCREENING AGENTS SOCIETE L'OREAL S.A. (FR) 2003-08-14 US claimed
US-20030129152-A1 STABLE/IMPROVEDLY SELF-TANNING COMPOSITIONS COMPRISING AMINO-SUBSTITUTED 2-HYDROXYBENZOPHENONE COMPOUNDS SOCIETE L'OREAL S.A. (FR) 2003-07-10 US claimed
CN-117903102-B Fluorescent probe and preparation method and application thereof 曲阜师范大学 2024-06-28 CN disclosed
CN-117903102-B Fluorescent probe and preparation method and application thereof 曲阜师范大学 2024-06-28 CN disclosed
CN-117903102-A Fluorescent probe and preparation method and application thereof 曲阜师范大学 2024-04-19 CN disclosed
CN-1273088-A Use of amino-substituted hydroxybenzophenones as photostable UV filters in cosmetic and pharmaceutical preparations BASF AG (DE) 2000-11-15 CN disclosed
EP-1046391-A2 Use of aminosubstituted hydroxybenzophenones as photostable UV-filters in cosmetic and pharmaceutical preparations BASF AKTIENGESELLSCHAFT (DE) 2000-10-25 EP disclosed
US-4260776-A PYRAZOLONE BAYER AKTIENGESELLSCHAFT (DE) 1981-04-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030180230-A1 UV-photostabilized sunscreen compositions comprising dibenzoylmethane/triazine/benzophenone compounds DHPS, WEE2, DDT MEN1 2042/4885KMT2A 1829/4885SMN1; SMN2 4837/4885
US-20030161793-A1 UV-photostabilized sunscreen compositions comprising dibenzoylmethane/benzophenone compounds HADHB, HADH, NOTUM MEN1 1236/4885KMT2A 2759/4885SMN1; SMN2 4765/4885
US-20030161794-A1 Synergistically UV-photoprotecting sunscreen compositions comprising camphorsulfonic acid/benzophenone compounds HADH, HADHB, BCAS2 MEN1 3392/4885KMT2A 4384/4885SMN1; SMN2 4668/4885
US-20030129152-A1 STABLE/IMPROVEDLY SELF-TANNING COMPOSITIONS COMPRISING AMINO-SUBSTITUTED 2-HYDROXYBENZOPHENONE COMPOUNDS TYR, MITF, CYP51A1 MEN1 2189/4885KMT2A 1140/4885SMN1; SMN2 4177/4885
US-20030157038-A1 SYNERGISTICALLY UV-PHOTOPROTECTING MIXED SUNSCREEN COMPOSITIONS PSAT1, TST, BPTF MEN1 2234/4885KMT2A 3045/4885SMN1; SMN2 4481/4885
US-20030152532-A1 SYNERGISTICALLY UV-PHOTOPROTECTING COMPOSITIONS COMPRISING MIXED SCREENING AGENTS HADHB, SDHA, ERCC4 MEN1 3716/4885KMT2A 3626/4885SMN1; SMN2 4816/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.