Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRC | Q99895 | 1/20 | 0.68 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.68 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.68 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 5/20 | 0.60 |
| ▸ | GAA | P10253 | 5/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15127235 | 1.00 | CTRC (0.68) | CTRCDUSP3PTPN5PTPN11KDM4E | |
| SCHEMBL6635848 | 1.00 | CTRC (0.68) | CTRCDUSP3PTPN5PTPN11KDM4E | |
| SCHEMBL2964189 | 0.85 | CTRC (0.74) | CTRCDUSP3PTPN5PTPN11KDM4E | |
| SCHEMBL2964190 | 0.85 | CTRC (0.74) | CTRCDUSP3PTPN5PTPN11KDM4E | |
| SCHEMBL31035857 | 0.85 | CTRC (0.74) | CTRCDUSP3PTPN5PTPN11KDM4E | |
| SCHEMBL15275529 | 0.84 | KDM4E (0.76) | CTRCDUSP3PTPN5PTPN11KDM4E | |
| SCHEMBL18850756 | 0.84 | CTRC (0.68) | CTRCDUSP3PTPN5PTPN11KDM4E | |
| SCHEMBL16141587 | 0.83 | CTRC (0.62) | CTRCDUSP3PTPN5PTPN11KDM4E | |
| SCHEMBL9967755 | 0.83 | CTRC (0.62) | CTRCDUSP3PTPN5PTPN11KDM4E | |
| SCHEMBL6633349 | 0.83 | HTT (0.70) | CTRCDUSP3PTPN5PTPN11KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0909788-B1 | RUBBER COMPOSITION AND PNEUMATIC TIRES | BRIDGESTONE CORP (JP) | 2004-12-01 | — | — | EP | disclosed |
| EP-1420044-A2 | Rubber composition and pneumatic tire | Bridgestone Corporation (JP) | 2004-05-19 | — | — | EP | disclosed |
| EP-0909788-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRES | Bridgestone Corporation (JP) | 1999-04-21 | — | — | EP | disclosed |