SCHEMBL2964189

SCHEMBL2964189

CC(=O)N/N=C/c1ccccc1O

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTRC Q99895 1/20 0.74
DUSP3 P51452 1/20 0.74
PTPN5 P54829 1/20 0.74
PTPN11 Q06124 1/20 0.74
KDM4E B2RXH2 5/20 0.66
KMT2A Q03164 4/20 0.66
MEN1 O00255 3/20 0.66
TP53 P04637 1/20 0.66
CYP3A4 P08684 1/20 0.66
CYP2D6 P10635 1/20 0.66
HPGD P15428 1/20 0.66
MAPK1 P28482 1/20 0.66
HSD17B10 Q99714 1/20 0.66
TDP1 Q9NUW8 1/20 0.66
KDM1A O60341 3/20 0.62
MAOA P21397 1/20 0.62
MAOB P27338 1/20 0.62
L3MBTL1 Q9Y468 2/20 0.60
GAA P10253 1/20 0.60
NPC1 O15118 3/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2964190 1.00 CTRC (0.74) CTRCDUSP3PTPN5PTPN11KDM4E
SCHEMBL31035857 1.00 CTRC (0.74) CTRCDUSP3PTPN5PTPN11KDM4E
SCHEMBL8848959 0.86 NOX4 (0.76) CTRCDUSP3PTPN5PTPN11KDM4E
SCHEMBL8848964 0.86 NOX4 (0.76) CTRCDUSP3PTPN5PTPN11KDM4E
SCHEMBL15457448 0.85 DUSP3 (1.00) CTRCDUSP3PTPN5PTPN11KDM4E
SCHEMBL6635848 0.85 CTRC (0.68) CTRCDUSP3PTPN5PTPN11KDM4E
SCHEMBL6635845 0.85 CTRC (0.68) CTRCDUSP3PTPN5PTPN11KDM4E
SCHEMBL15127235 0.85 CTRC (0.68) CTRCDUSP3PTPN5PTPN11KDM4E
SCHEMBL20837852 0.84 CTRC (0.77) CTRCDUSP3PTPN5PTPN11KDM4E
SCHEMBL20837851 0.84 CTRC (0.77) CTRCDUSP3PTPN5PTPN11KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1994385-B1 CHANGED CONDITION INDICATOR COOPERMAN ISADORE (US) 2019-08-14 EP disclosed
US-7770534-B2 Changed condition indicator THERMOPROX 2010-08-10 US disclosed
EP-1994385-A2 CHANGED CONDITION INDICATOR Cooperman, Isadore (US) 2008-11-26 EP disclosed
WO-2007106463-A2 CHANGED CONDITION INDICATOR COOPERMAN ISADORE (US) 2007-09-20 WO disclosed
US-20070151502-A1 Changed condition indicator THERMOPROX 2007-07-05 US disclosed
EP-0764685-A2 Polymer solutions COURTAULDS FIBRES (HOLDINGS) LIMITED (GB) 1997-03-26 EP disclosed