Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 8/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6634360 | 0.79 | MTNR1A (0.44) | MTNR1AMTNR1B | |
| SCHEMBL6633679 | 0.78 | MTNR1A (0.58) | MTNR1AMTNR1B | |
| SCHEMBL5379988 | 0.73 | CYP11B1 (0.44) | MTNR1AMTNR1BNSD2CASP6GFER | |
| SCHEMBL6634046 | 0.69 | MTNR1A (0.44) | MTNR1AMTNR1B | |
| SCHEMBL6635809 | 0.68 | MTNR1A (0.46) | MTNR1AMTNR1B | |
| SCHEMBL6638132 | 0.67 | MTNR1A (0.42) | MTNR1AMTNR1B | |
| SCHEMBL28814019 | 0.66 | FYN (0.48) | MTNR1AMTNR1BCYP3A4TSHR | |
| SCHEMBL29593942 | 0.66 | HTR2A (0.52) | — | |
| SCHEMBL714536 | 0.66 | HTR2A (0.52) | — | |
| SCHEMBL27802966 | 0.66 | MTNR1A (0.36) | MTNR1AMTNR1BNSD2CASP6GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047664-B1 | NOVEL TRICYCLIC COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2004-05-19 | — | — | EP | disclosed |
| US-6423870-B1 | ANTICOAGULANTS; CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS | LES LABORATOIRES SERVIER (FR) | 2002-07-23 | — | — | US | disclosed |