Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 8/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6638132 | 0.92 | MTNR1A (0.42) | MTNR1AMTNR1BCYP19A1 | |
| SCHEMBL6634360 | 0.89 | MTNR1A (0.44) | MTNR1AMTNR1BCYP19A1HTR2A | |
| SCHEMBL7735732 | 0.80 | MTNR1A (0.49) | MTNR1AMTNR1B | |
| SCHEMBL10616643 | 0.79 | ADRA1A (0.59) | MTNR1AMTNR1B | |
| SCHEMBL6635290 | 0.78 | MTNR1A (0.62) | MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL10615473 | 0.78 | ADRA1A (0.57) | MTNR1AMTNR1B | |
| SCHEMBL6636157 | 0.77 | MTNR1B (0.65) | MTNR1AMTNR1B | |
| SCHEMBL6638097 | 0.77 | MTNR1A (0.67) | MTNR1AMTNR1B | |
| SCHEMBL6634680 | 0.77 | MTNR1A (0.52) | MTNR1AMTNR1B | |
| SCHEMBL10615302 | 0.74 | CHRM2 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047664-B1 | NOVEL TRICYCLIC COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2004-05-19 | — | — | EP | disclosed |
| US-6423870-B1 | ANTICOAGULANTS; CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS | LES LABORATOIRES SERVIER (FR) | 2002-07-23 | — | — | US | disclosed |