Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | SRC | P12931 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9139033 | 0.84 | CYP2C19 (0.52) | CYP2C19SRCCYP2D6LMNAKMT2A | |
| SCHEMBL2392454 | 0.80 | KMT2A (0.43) | CYP2C19SRCCYP2D6LMNAKMT2A | |
| SCHEMBL14678298 | 0.76 | CYP2C19 (0.44) | CYP2C19KMT2AALDH1A1KDM4E | |
| SCHEMBL6639307 | 0.72 | LMNA (0.42) | CYP2C19SRCCYP2D6LMNAALDH1A1 | |
| SCHEMBL3910710 | 0.71 | CYP2C19 (1.00) | CYP2C19SRCCYP2D6LMNAMAPK1 | |
| SCHEMBL496890 | 0.70 | SRC (0.58) | CYP2C19SRCCYP2D6LMNAMAPK1 | |
| SCHEMBL3221517 | 0.69 | CYP2C19 (0.41) | CYP2C19SRCLMNA | |
| SCHEMBL780336 | 0.69 | CYP2C19 (0.52) | CYP2C19SRCCYP2D6LMNAMAPK1 | |
| SCHEMBL9244633 | 0.69 | SRC (0.56) | CYP2C19SRCCYP2D6LMNAMAPK1 | |
| SCHEMBL8360847 | 0.69 | SRC (0.56) | CYP2C19SRCCYP2D6LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12324859-B2 | Compounds and compositions for intracellular delivery of therapeutic agents | MODERNATX, INC. (US) | 2025-06-10 | — | — | US | disclosed |
| US-20210154148-A1 | COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS | ARES CAPITAL CORPORATION, AS AGENT | 2021-05-27 | — | — | US | disclosed |
| EP-0934303-B1 | COMPOUNDS USEFUL FOR INHIBITION OF FARNESYL PROTEIN TRANSFERASE | SCHERING CORP (US) | 2004-12-29 | — | — | EP | disclosed |
| EP-0927178-B1 | TRICYCLIC COMPOUNDS USEFUL FOR INHIBITION OF G-PROTEIN FUNCTION AND FOR TREATMENT OF PROLIFERATIVE DISEASES | SCHERING CORP (US) | 2002-02-27 | — | — | EP | disclosed |
| US-5958890-A | ANTITUMOR | SCHERING CORPORATION (US) | 1999-09-28 | — | — | US | disclosed |
| EP-0934303-A2 | COMPOUNDS USEFUL FOR INHIBITION OF FARNESYL PROTEIN TRANSFERASE | SCHERING CORPORATION (US) | 1999-08-11 | — | — | EP | disclosed |
| US-5861395-A | ENZYME INHIBITORS FOR BREAST TUMOR CELLS | SCHERING CORPORATION (US) | 1999-01-19 | — | — | US | disclosed |
| WO-1998011091-A2 | TRICYCLIC COMPOUNDS USEFUL FOR INHIBITION OF FARNESYL PROTEIN TRANSFERASE | SCHERING CORPORATION (US) | 1998-03-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12324859-B2 | Compounds and compositions for intracellular delivery of therapeutic agents | LNPK, PLTP, PLIN3 | CYP2C19 4882/4885SRC 2436/4885CYP2D6 4804/4885 |
| US-20210154148-A1 | COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS | LNPK, PLTP, PLIN3 | CYP2C19 4882/4885SRC 2436/4885CYP2D6 4804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.