Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 8/20 | 0.57 |
| ▸ | PPARG | P37231 | 11/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6633896 | 0.94 | F2 (0.65) | F2PDE10AF10ITGB3ITGA2B | |
| SCHEMBL6635937 | 0.88 | PPARG (0.47) | F2PPARGPDE10A | |
| SCHEMBL6640819 | 0.85 | F2 (0.76) | F2PDE10AF10 | |
| SCHEMBL6636052 | 0.83 | F2 (0.43) | F2F10ITGB3ITGA2B | |
| SCHEMBL6635191 | 0.83 | F2 (0.44) | F2PDE10AF10ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL8029579 | 0.82 | F2 (0.70) | F2F10 | |
| SCHEMBL6634233 | 0.82 | F2 (0.62) | F2F10 | |
| SCHEMBL6638617 | 0.81 | F2 (0.49) | F2PPARGPDE10A | |
| SCHEMBL6639400 | 0.81 | F2 (0.63) | F2F10 | |
| SCHEMBL6639091 | 0.81 | F2 (0.84) | F2PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100795-B1 | DISUBSTITUTED BICYCLIC HETEROCYCLES HAVING, IN PARTICULAR, A THROMBIN INHIBITIVE EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-06-09 | — | — | EP | disclosed |