⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16015603 | 1.00 | — | — | |
| SCHEMBL15835816 | 1.00 | — | — | |
| SCHEMBL13411703 | 0.87 | KDM4E (0.43) | — | |
| SCHEMBL18212161 | 0.81 | LMNA (0.33) | — | |
| SCHEMBL18212163 | 0.81 | LMNA (0.33) | — | |
| SCHEMBL24371945 | 0.81 | PAOX (0.38) | — | |
| SCHEMBL18212159 | 0.81 | LMNA (0.33) | — | |
| SCHEMBL1436205 | 0.80 | — | — | |
| SCHEMBL5206473 | 0.80 | — | — | |
| SCHEMBL3459825 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4630410-A1 | POLQ INHIBITORS | Astrazeneca AB (SE) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024121753-A1 | POLQ INHIBITORS | ASTRAZENECA AB (SE) | 2024-06-13 | — | — | WO | disclosed |
| US-20230339945-A1 | METHOD FOR PREPARING A CHELATING LIGAND DERIVED FROM PCTA | GUERBET (FR) | 2023-10-26 | — | — | US | disclosed |
| EP-3498724-B1 | NUCLEIC ACID COMPLEX | KYOWA KIRIN CO LTD (JP) | 2023-06-21 | — | — | EP | disclosed |
| WO-2023072974-A1 | TRICYCLIC HETEROCYCLES | MERCK PATENT GMBH (DE) | 2023-05-04 | — | — | WO | disclosed |
| US-20230127655-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-04-27 | — | — | US | disclosed |
| US-11591341-B2 | Bicyclic and tricyclic compounds | ALIGOS THERAPEUTICS, INC. (US) | 2023-02-28 | — | — | US | disclosed |
| EP-3988547-A1 | INDAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATION THEREOF | Jiangsu Hengrui Medicine Co., Ltd. (CN) | 2022-04-27 | — | — | EP | disclosed |
| EP-3888663-A1 | NUCLEIC ACID COMPLEX | Kyowa Kirin Co., Ltd. (JP) | 2021-10-06 | — | — | EP | disclosed |
| US-20200361947-A1 | BICYCLIC AND TRICYCLIC COMPOUNDS | ALIGOS THERAPEUTICS, INC. | 2020-11-19 | — | — | US | disclosed |
| EP-3498724-A1 | NUCLEIC ACID COMPLEX | Kyowa Hakko Kirin Co., Ltd. (JP) | 2019-06-19 | — | — | EP | disclosed |
| EP-3091011-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | Vertex Pharmaceuticals Inc. (US) | 2016-11-09 | — | — | EP | disclosed |
| EP-2674428-B1 | Modulators of ATP-binding cassette transporters | VERTEX PHARMA (US) | 2016-04-06 | — | — | EP | disclosed |
| US-20150344457-A1 | METHODS OF INHIBITING PRMT5 | Epizyme, Inc. (US) | 2015-12-03 | — | — | US | disclosed |
| US-8921373-B2 | Compounds having TRPV1 antagonistic activity and uses thereof | SHIONOGI & CO., LTD. (JP) | 2014-12-30 | — | — | US | disclosed |
| EP-1067894-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2004-09-08 | — | — | EP | disclosed |
| EP-1067894-A2 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2001-01-17 | — | — | EP | disclosed |
| WO-1999059526-A2 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-11-25 | — | — | WO | disclosed |