Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.79 |
| ▸ | CA9 | Q16790 | 4/20 | 0.79 |
| ▸ | L1CAM | P32004 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | MPO | P05164 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 7/20 | 0.61 |
| ▸ | RAB9A | P51151 | 5/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL77381 | 0.91 | CA1 (0.77) | CA1CA9L1CAMKDM4ESMN1; SMN2 | |
| SCHEMBL28850791 | 0.88 | CA1 (1.00) | CA1CA9L1CAMKDM4ESMN1; SMN2 | |
| SCHEMBL5456246 | 0.86 | CA1 (0.71) | CA1CA9L1CAMKDM4ESMN1; SMN2 | |
| SCHEMBL29851354 | 0.82 | CA1 (0.65) | CA1CA9L1CAMKDM4ESMN1; SMN2 | |
| SCHEMBL6638020 | 0.82 | NPC1 (0.74) | CA1CA9L1CAMKDM4ESMN1; SMN2 | |
| SCHEMBL23978398 | 0.82 | KDM4E (0.65) | CA1CA9L1CAMKDM4ESMN1; SMN2 | |
| SCHEMBL1169719 | 0.82 | CA1 (0.65) | CA1CA9L1CAMKDM4ESMN1; SMN2 | |
| SCHEMBL4218154 | 0.82 | CA1 (0.65) | CA1CA9L1CAMKDM4ESMN1; SMN2 | |
| SCHEMBL6448644 | 0.80 | CA1 (0.62) | CA1CA9L1CAMKDM4ESMN1; SMN2 | |
| SCHEMBL8722405 | 0.80 | CA1 (0.72) | CA1CA9L1CAMKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1420044-A2 | Rubber composition and pneumatic tire | Bridgestone Corporation (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-6380288-B1 | LOW HEAT GENERATION PROPERTY, AGING REISTANCE, ALSO FOR PRODUCING VIBRATION ISOLATORS, BELTS AND HOSES AS WELL AS TIRE MATERIALS SUCH AS TIRE TREADS, UNDERTREADS, CARCASSES, SIDE WALLS AND BEADS | BRIDGESTONE CORPORATION | 2002-04-30 | — | — | US | disclosed |
| EP-0909788-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRES | Bridgestone Corporation (JP) | 1999-04-21 | — | — | EP | disclosed |