SCHEMBL77381

SCHEMBL77381

O=C(NNC(=O)c1ccccc1O)c1ccccc1O

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.77
CA9 Q16790 4/20 0.77
L1CAM P32004 1/20 0.71
KDM4E B2RXH2 4/20 0.71
SMN1; SMN2 Q16637 2/20 0.71
GAA P10253 2/20 0.71
MPO P05164 1/20 0.71
HIF1A Q16665 1/20 0.71
NPC1 O15118 7/20 0.69
RAB9A P51151 5/20 0.69
HTT P42858 3/20 0.69
ALDH1A1 P00352 1/20 0.69
CYP2D6 P10635 1/20 0.69
CYP2C9 P11712 1/20 0.69
LMNA P02545 3/20 0.64
TP53 P04637 2/20 0.63
MEN1 O00255 2/20 0.63
KMT2A Q03164 2/20 0.63
HPGD P15428 1/20 0.63
HSD17B10 Q99714 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6636585 0.91 CA1 (0.79) CA1CA9L1CAMKDM4ESMN1; SMN2
SCHEMBL6638020 0.89 NPC1 (0.74) CA1CA9L1CAMKDM4ESMN1; SMN2
SCHEMBL1169719 0.89 CA1 (0.65) CA1CA9L1CAMKDM4ESMN1; SMN2
SCHEMBL29851354 0.89 CA1 (0.65) CA1CA9L1CAMKDM4ESMN1; SMN2
SCHEMBL4218154 0.89 CA1 (0.65) CA1CA9L1CAMKDM4ESMN1; SMN2
SCHEMBL23978398 0.89 KDM4E (0.65) CA1CA9L1CAMKDM4ESMN1; SMN2
SCHEMBL6448644 0.88 CA1 (0.62) CA1CA9L1CAMKDM4ESMN1; SMN2
SCHEMBL28850791 0.88 CA1 (1.00) CA1CA9L1CAMKDM4ESMN1; SMN2
SCHEMBL8015608 0.87 CA1 (0.61) CA1CA9L1CAMKDM4ESMN1; SMN2
SCHEMBL5456246 0.86 CA1 (0.71) CA1CA9L1CAMKDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3761 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116515168-A Copper ion migration inhibitor, PBT composite material and preparation method thereof 株洲时代新材料科技股份有限公司 2023-08-01 CN claimed
EP-3428229-B1 CURABLE RESIN COMPOSITION, FUEL CELL, AND SEALING METHOD THREE BOND CO LTD (JP) 2022-08-17 EP claimed
US-10800952-B2 Curable resin composition, fuel cell, and sealing method THREEBOND CO., LTD. (JP) 2020-10-13 US claimed
EP-2920236-B1 POLYMER COMPOSITION HAVING IMPROVED LONG-TERM STABILITY, MOULDED PARTS PRODUCED THEREFROM AND INTENDED USES THEREOF FRAUNHOFER GES FORSCHUNG (DE) 2019-06-05 EP claimed
EP-3166999-A1 THERMAL INTERFACE MATERIAL WITH ION SCAVENGER Honeywell International Inc. (US) 2017-05-17 EP claimed
US-20160272789-A1 POLYMER COMPOSITION WITH IMPROVED LONG-TERM STABILITY, MOULDED PARTS PRODUCED HEREFROM AND ALSO PURPOSES OF USE FRAUNHOFER-GESELLACHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 2016-09-22 US claimed
WO-2016004565-A1 THERMAL INTERFACE MATERIAL WITH ION SCAVENGER HONEYWELL INTERNATIONAL INC. (US) 2016-01-14 WO claimed
EP-2920236-A1 POLYMER COMPOSITION HAVING IMPROVED LONG-TERM STABILITY, MOULDED PARTS PRODUCED THEREFROM AND INTENDED USES THEREOF FRAUNHOFER-GESELLSCHAFT zur Förderung der angewandten Forschung e.V. (DE) 2015-09-23 EP claimed
WO-2014076273-A1 POLYMER COMPOSITION HAVING IMPROVED LONG-TERM STABILITY, MOULDED PARTS PRODUCED THEREFROM AND INTENDED USES THEREOF Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2014-05-22 WO claimed
EP-1676887-B1 Composition and process for improving heat and weathering stability of segmented polyurethane polymers CIBA SC HOLDING AG (CH) 2007-05-23 EP claimed
EP-0127054-A2 Stabilization of organic polymer materials SIEMENS AKTIENGESELLSCHAFT (DE) 1984-12-05 EP claimed
US-4472700-A Transformer with copper windings, liquid insulation material and supply depot containing solid copper deactivator to prevent dissolution of the copper SIEMENS AKTIENGESELLSCHAFT (DE) 1984-09-18 US claimed
EP-0047423-B1 PROCESS FOR PREPARING N.N'-BIS-SALICYLOYL HYDRAZINE AND ITS USE SIEMENS AKTIENGESELLSCHAFT (DE) 1984-05-02 EP claimed
US-4446266-A N,N'-Bis-salicyloyl-hydrazine as a metal deactivator SIEMENS AKTIENGESELLSCHAFT (DE) 1984-05-01 US claimed
US-4418170-A N,N-BIS-SALTIYLOYL HYDRAZINE PASTES SIEMENS AKTIENGESELLSCHAFT (DE) 1983-11-29 US claimed
EP-0090216-A1 Process and apparatus for the preparation of N,N'-bis-aroyl hydrazines SIEMENS AKTIENGESELLSCHAFT (DE) 1983-10-05 EP claimed
EP-0071849-A1 Process for stabilizing organic polymers against oxidative degradation SIEMENS AKTIENGESELLSCHAFT (DE) 1983-02-16 EP claimed
EP-0025505-A2 N.N'-Bis-salicyloyl hydrazine as metal stabilizer SIEMENS AKTIENGESELLSCHAFT (DE) 1981-03-25 EP claimed
US-3994987-A Metal deactivators as adhesion promotors for vulcanizable elastomers to metals CIBA-GEIGY CORPORATION (US) 1976-11-30 US claimed
US-3993622-A Bis-salicyloyl-hydrazine as stabilizer for polymers CIBA-GEIGY CORPORATION (US) 1976-11-23 US claimed