Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 11/20 | 0.43 |
| ▸ | HTR2A | P28223 | 11/20 | 0.43 |
| ▸ | HTR7 | P34969 | 11/20 | 0.43 |
| ▸ | HTR6 | P50406 | 11/20 | 0.43 |
| ▸ | PGR | P06401 | 3/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | IP6K1 | Q92551 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6634875 | 0.81 | HTR7 (0.41) | HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL17806129 | 0.77 | PGR (0.46) | PGRIP6K1 | |
| SCHEMBL6634486 | 0.77 | HTR7 (0.44) | HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL6638270 | 0.76 | HTR7 (0.60) | HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL6636447 | 0.76 | HTR7 (0.60) | HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL6635868 | 0.76 | HTR7 (0.60) | HTR1AHTR2AHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL6635087 | 0.76 | HTR7 (0.43) | HTR1AHTR2AHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL6747853 | 0.76 | HTR7 (0.43) | HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL30540607 | 0.75 | PGR (0.42) | HTR1AHTR2AHTR7HTR6PGR | |
| Hydrochloric Acid SCHEMBL6639494 | 0.75 | HTR7 (0.59) | HTR1AHTR2AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202994-B1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 2004-04-14 | — | — | EP | claimed |