Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27549844 | 0.94 | KIF11 (0.69) | KIF11EPHX2KMT2AMEN1EPHX1 | |
| SCHEMBL23493346 | 0.83 | EPHX2 (0.57) | EPHX2KMT2AMAPTTRPV1GAA | |
| SCHEMBL10339425 | 0.83 | EPHX2 (0.57) | EPHX2KMT2AMEN1MAPTTRPV1 | |
| SCHEMBL6284986 | 0.82 | KMT2A (0.64) | KIF11KMT2AMEN1MAPTPOLB | |
| SCHEMBL5239776 | 0.81 | KMT2A (0.71) | KIF11KMT2AMEN1EPHX1MAPT | |
| SCHEMBL4316832 | 0.79 | KIF11 (0.89) | KIF11EPHX2KMT2AMEN1TRPV1 | |
| SCHEMBL3960405 | 0.79 | LMNA (0.57) | EPHX2KMT2AMEN1MAPTTRPV1 | |
| SCHEMBL324161 | 0.79 | PARP10 (0.59) | EPHX2KMT2ATRPV1NPC1RAB9A | |
| SCHEMBL6667143 | 0.79 | KIF11 (0.50) | KIF11KMT2AMEN1MAPTRAB9A | |
| SCHEMBL28909073 | 0.78 | KIF11 (0.86) | KIF11EPHX2KMT2AMEN1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109535036-A | A kind of synthetic method of indoxacarb intermediate chloroformyl [4- (trifluoromethoxy) phenyl] methyl carbamate | 山东华阳农药化工集团有限公司 | 2019-03-29 | — | — | CN | claimed |
| US-6087358-A | BACTERICIDES TREATING PATHOGENIC INFECTIONS OF MYCOBACTERIA, CLOSTRIDIUM, CRYPTOSPORIDIUM OR HELICOBACTER AND MULTIDRUG-RESISTANT TUBERCULOSIS | PATHOGENESIS CORPORATION (US) | 2000-07-11 | — | — | US | claimed |
| CN-117940402-A | Method for producing arthropodicidal oxadiazine intermediates | 安道麦马克西姆有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-117242060-A | Isoindolinone compounds | 蒙特罗萨医疗公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-113347883-B | Pesticidal compositions and methods | 科迪华农业科技有限责任公司 | 2023-11-03 | — | — | CN | disclosed |
| CN-115335039-A | Caspase 6 inhibitors and uses thereof | 加利福尼亚大学董事会 | 2022-11-11 | — | — | CN | disclosed |
| CN-113347883-A | Pesticidal compositions and methods | 科迪华农业科技有限责任公司 | 2021-09-03 | — | — | CN | disclosed |
| CN-109704994-A | A kind of improved method synthesizing indoxacarb intermediate chloroformyl [4- (trifluoromethoxy) phenyl] methyl carbamate | 山东华阳农药化工集团有限公司 | 2019-05-03 | — | — | CN | disclosed |
| CN-109535036-A | A kind of synthetic method of indoxacarb intermediate chloroformyl [4- (trifluoromethoxy) phenyl] methyl carbamate | 山东华阳农药化工集团有限公司 | 2019-03-29 | — | — | CN | disclosed |
| CN-108840986-A | Carbonic ester-carbamic acid mixed ester method is prepared based on cellulose carbonic ester | 贵州大学 | 2018-11-20 | — | — | CN | disclosed |
| CN-103936630-B | The preparation method of chloroformyl [4-(trifluoromethoxy) phenyl] Urethylane | JINGBO AGROCHEMICALS TECHNOLOGY Co.,Ltd. (CN) | 2015-10-07 | — | — | CN | disclosed |
| CN-103936630-A | Method for preparing chlorocarbonyl[4-(trifluoromethoxy)phenyl] methyl carbamate | JINGBO AGROCHEMICALS TECHNOLOGY CO LTD | 2014-07-23 | — | — | CN | disclosed |
| CN-103910653-A | Preparation method of chlorocarbonyl[4-(trifluoromethoxy)phenyl]methyl carbamate | JINGBO AGROCHEMICALS TECHNOLOGY CO LTD | 2014-07-09 | — | — | CN | disclosed |
| EP-0866793-B1 | NITROIMIDAZOLE ANTIBACTERIAL COMPOUNDS AND METHODS OF USE THEREOF | CHIRON CORP (US) | 2004-10-27 | — | — | EP | disclosed |
| US-6087358-A | BACTERICIDES TREATING PATHOGENIC INFECTIONS OF MYCOBACTERIA, CLOSTRIDIUM, CRYPTOSPORIDIUM OR HELICOBACTER AND MULTIDRUG-RESISTANT TUBERCULOSIS | PATHOGENESIS CORPORATION (US) | 2000-07-11 | — | — | US | disclosed |
| EP-0866793-A4 | — | — | 1998-10-07 | — | — | EP | disclosed |
| EP-0866793-A1 | NITROIMIDAZOLE ANTIBACTERIAL COMPOUNDS AND METHODS OF USE THEREOF | PATHOGENESIS CORPORATION (US) | 1998-09-30 | — | — | EP | disclosed |
| WO-1997001562-A1 | NITROIMIDAZOLE ANTIBACTERIAL COMPOUNDS AND METHODS OF USE THEREOF | PATHOGENESIS CORPORATION (US) | 1997-01-16 | — | — | WO | disclosed |