Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 19/20 | 0.50 |
| ▸ | NR3C2 | P08235 | 11/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14587244 | 0.80 | NR3C2 (0.54) | NR3C1NR3C2PGR | |
| SCHEMBL4483365 | 0.80 | NR3C2 (0.54) | NR3C1NR3C2PGR | |
| SCHEMBL14157329 | 0.79 | ALDH1A1 (0.47) | NR3C1NR3C2 | |
| SCHEMBL3882399 | 0.76 | NR3C2 (0.53) | NR3C1NR3C2PGR | |
| SCHEMBL16935946 | 0.75 | SLC6A2 (0.62) | — | |
| SCHEMBL1634957 | 0.75 | NR3C1 (0.48) | NR3C1NR3C2PGR | |
| SCHEMBL278306 | 0.73 | NR3C2 (0.49) | NR3C1NR3C2 | |
| SCHEMBL1634108 | 0.73 | HTR2C (0.46) | NR3C1NR3C2 | |
| SCHEMBL14157327 | 0.73 | NR3C2 (0.43) | NR3C1NR3C2 | |
| SCHEMBL6643467 | 0.73 | NR3C1 (0.47) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490317-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2004-12-29 | — | — | EP | disclosed |
| EP-1490062-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2004-12-29 | — | — | EP | disclosed |
| WO-2003082280-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2003-10-09 | — | — | WO | disclosed |
| WO-2003082787-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2003-10-09 | — | — | WO | disclosed |