Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL331867 | 0.83 | TSHR (0.38) | TSHRTHRB | |
| SCHEMBL759924 | 0.83 | TSHR (0.34) | TSHRTHRB | |
| SCHEMBL332529 | 0.82 | — | — | |
| SCHEMBL663826 | 0.82 | — | — | |
| SCHEMBL755621 | 0.80 | TSHR (0.37) | TSHRTHRB | |
| SCHEMBL35615 | 0.80 | TSHR (0.46) | TSHRTHRB | |
| SCHEMBL663825 | 0.79 | TSHR (0.36) | TSHRTHRB | |
| SCHEMBL12799607 | 0.78 | TSHR (0.35) | TSHRTHRB | |
| SCHEMBL3679702 | 0.77 | TSHR (0.38) | TSHR | |
| SCHEMBL663827 | 0.77 | TSHR (0.35) | TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8263679-B2 | Prepolymers with dangling polysiloxane-containing polymer chains | NOVARTIS AG (CH) | 2012-09-11 | — | — | US | claimed |
| US-20120046382-A1 | PREPOLYMERS WITH DANGLING POLYSILOXANE-CONTAINING POLYMER CHAINS | ALCON INC. (CH) | 2012-02-23 | — | — | US | claimed |
| US-8071658-B2 | Prepolymers with dangling polysiloxane-containing polymer chains | NOVARTIS AG (CH) | 2011-12-06 | — | — | US | claimed |
| JP-2010522265-A | — | — | 2010-07-01 | — | — | JP | claimed |
| EP-2129513-A2 | PREPOLYMERS WITH DANGLING POLYSILOXANE-CONTAINING POLYMER CHAINS | Novartis Ag (CH) | 2009-12-09 | — | — | EP | claimed |
| WO-2008116131-A2 | PREPOLYMERS WITH DANGLING POLYSILOXANE-CONTAINING POLYMER CHAINS | NOVARTIS AG (CH) | 2008-09-25 | — | — | WO | claimed |
| US-20080231798-A1 | Prepolymers with dangling polysiloxane-containing polymer chains | ALCON INC. (CH) | 2008-09-25 | — | — | US | claimed |
| EP-3052140-B1 | NON-SELF-ADHERENT COATING MATERIALS | ROCHAL IND LLC (US) | 2019-05-01 | — | — | EP | disclosed |
| US-8877882-B1 | Non-self-adherent coating materials | ROCHAL INDUSTRIES LLP (US) | 2014-11-04 | — | — | US | disclosed |