SCHEMBL331867

SCHEMBL331867

C=C(C)C(=O)OCC(O)COCCC[SiH2]C(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.38
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30386461 0.89 TSHR (0.38) TSHRTHRB
SCHEMBL35420 0.87 USP2 (0.32)
SCHEMBL30170509 0.85 TSHR (0.40) TSHR
SCHEMBL35615 0.84 TSHR (0.46) TSHRTHRB
SCHEMBL23493061 0.83 TSHR (0.38) TSHRTHRB
Methacrylic Acid SCHEMBL2125330 0.83 USP2 (0.38)
SCHEMBL663828 0.83 TSHR (0.34) TSHRTHRB
SCHEMBL508665 0.81
SCHEMBL509069 0.81
SCHEMBL16864281 0.80 TSHR (0.45) TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 797 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122043786-A Therapeutic cornea contact lens with far infrared function 中国人民解放军总医院第三医学中心 2026-05-15 CN claimed
US-20260042269-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES ALCON INC (CH) 2026-02-12 US claimed
US-20260042268-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES ALCON INC (CH) 2026-02-12 US claimed
EP-4683962-A1 MONOFUNCTIONAL SILICONE MONOMERS AND SILICONE HYDROGELS FORMED THEREFROM Bausch + Lomb Ireland Limited (IE) 2026-01-28 EP claimed
EP-4657145-A2 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES Alcon Inc. (CH) 2025-12-03 EP claimed
EP-4657144-A2 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES Alcon Inc. (CH) 2025-12-03 EP claimed
EP-4652144-A1 PHOTOCURABLE SOL-GEL COMPOSITIONS D. Swarovski KG (AT) 2025-11-26 EP claimed
US-20250223392-A1 HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF ALCON INC (CH) 2025-07-10 US claimed
US-12286501-B2 Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof ALCON INC. (CH) 2025-04-29 US claimed
CN-119875000-A Method for reducing the residual monomer content in a polymer composition, composition capable of free radical polymerization, method for producing a polymer, polymer and use 沈阳康恩德医疗科技有限公司 2025-04-25 CN claimed
EP-1560043-B1 Soft contact lenses JOHNSON & JOHNSON VISION CARE (US) 2008-06-18 EP claimed
US-20070229757-A1 BIOMEDICAL DEVICES CONTAINING INTERNAL WETTING AGENTS JOHNSON & JOHNSON VISION CARE, INC. 2007-10-04 US claimed
EP-1809344-A2 BIOMEDICAL DEVICES CONTAINING AMPHIPHILIC BLOCK COPOLYMERS Johnson and Johnson Vision Care, Inc. (US) 2007-07-25 EP claimed
US-7247692-B2 Biomedical devices containing amphiphilic block copolymers JOHNSON & JOHNSON VISION CARE, INC. (US) 2007-07-24 US claimed
WO-2006039467-A2 BIOMEDICAL DEVICES CONTAINING AMPHIPHILIC BLOCK COPOLYMERS JOHNSON & JOHNSON VISION CARE, INC. (US) 2006-04-13 WO claimed
US-20060074208-A1 Biomedical devices containing amphiphilic block copolymers JOHNSON & JOHNSON VISION CARE, INC. 2006-04-06 US claimed
EP-1641863-A2 SILICONE HYDROGELS HAVING CONSISTENT CONCENTRATIONS OF MULTI-FUNCTIONAL POLYSILOXANES Johnson & Johnson Vision Care, Inc. (US) 2006-04-05 EP claimed
US-20050255231-A1 Silicone hydrogels having consistent concentrations of multi-functional polysiloxanes JOHNSON & JOHNSON VISION CARE, INC. 2005-11-17 US claimed
EP-0940693-B1 Soft contact lenses JOHNSON & JOHNSON VISION CARE (US) 2005-06-22 EP claimed
WO-2005005517-A2 SILICONE HYDROGELS HAVING CONSISTENT CONCENTRATIONS OF MULTI-FUNCTIONAL POLYSILOXANES JOHNSON & JOHNSON VISION CARE, INC. (US) 2005-01-20 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260042269-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES CRYZ, STRA6, PHOSPHO1 TSHR 2055/4885THRB 2097/4885
US-20260042268-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES STRA6, CRYZ, SMCHD1 TSHR 1985/4885THRB 2866/4885
US-20050255231-A1 Silicone hydrogels having consistent concentrations of multi-functional polysiloxanes MMS19, FHIT, CAD TSHR 4175/4885THRB 2958/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.