Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31503776 | 0.71 | NR1H2 (0.38) | NR1H2MAPK1HSD11B1ALDH1A1 | |
| SCHEMBL29023069 | 0.71 | MAPT (0.47) | NR1H2MAPK1HSD11B1MEN1KMT2A | |
| SCHEMBL6884261 | 0.69 | MEN1 (0.39) | NR1H2MEN1KMT2ACHRM2CHRM1 | |
| SCHEMBL8610457 | 0.69 | NR1H2 (0.42) | NR1H2HSD11B1CHRM2CHRM1CHRM3 | |
| SCHEMBL16860460 | 0.69 | NR1H2 (0.39) | NR1H2MEN1KMT2ACHRM2CHRM1 | |
| SCHEMBL8611458 | 0.69 | NR1H2 (0.42) | NR1H2HSD11B1CHRM2CHRM1CHRM3 | |
| SCHEMBL20990302 | 0.66 | NR1H2 (0.39) | NR1H2MEN1KMT2ACHRM2CHRM1 | |
| SCHEMBL1398690 | 0.65 | HTT (0.43) | CHRM2CHRM1CHRM3 | |
| SCHEMBL1630474 | 0.65 | HTT (0.43) | CHRM2CHRM1CHRM3 | |
| SCHEMBL1630475 | 0.65 | HTT (0.43) | CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412078-A1 | PROCESSES FOR THE PRODUCTION OF AMINO-PROTECTED DERIVATIVES OF 4-AMINOMETHYLENE-PYRROLIDIN-3-ONE AND/OR 4-AMINOMETHYLENE-PYRROLIDIN-3-ALKOXYIMINO DERIVATIVES AND/OR GEMIFLOXACIN OR A SALT THEREOF | SB Pharmco Puerto Rico Inc (US) | 2004-04-28 | — | — | EP | disclosed |
| WO-2003011450-A1 | PROCESSES FOR THE PRODUCTION OF AMINO-PROTECTED DERIVATIVES OF 4-AMINOMETHYLENE-PYRROLIDIN-3-ONE AND/OR 4-AMINOMETHYLENE-PYRROLIDIN-3-ALKOXYIMINO DERIVATIVES AND/OR GEMIFLOXACIN OR A SALT THEREOF | LG LIFE SCIENCES LIMITED (KR) | 2003-02-13 | — | — | WO | disclosed |