Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7495913 | 0.81 | SLC6A3 (0.42) | SLC6A3DRD3LMNATP53CYP2D6 | |
| SCHEMBL7494831 | 0.81 | SLC6A3 (0.42) | SLC6A3DRD3LMNATP53CYP2D6 | |
| SCHEMBL7494352 | 0.74 | SLC6A3 (0.74) | SLC6A3TP53CYP2D6TSHRDRD2 | |
| SCHEMBL7544150 | 0.66 | SLC6A3 (0.61) | SLC6A3TP53CYP2D6TSHRDRD2 | |
| SCHEMBL7494600 | 0.66 | SLC6A3 (0.44) | SLC6A3 | |
| SCHEMBL7495367 | 0.66 | SLC6A3 (0.44) | SLC6A3DRD3ADRA2ADRD1DRD2 | |
| SCHEMBL9693133 | 0.63 | HTR2A (0.45) | TP53CYP2D6TSHRHTR1ADRD2 | |
| SCHEMBL6779110 | 0.63 | ANPEP (0.36) | TP53CYP2D6HTR2A | |
| SCHEMBL88255 | 0.62 | HTR2A (0.46) | SLC6A3DRD3LMNATP53CYP2D6 | |
| SCHEMBL8144693 | 0.61 | HTR2A (0.41) | SLC6A3DRD1SLC6A2SLC6A4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305318-B1 | PROCESS FOR THE PREPARATION OF 9-AMINO SUBSTITUTED 9,10-DIHYDROPYRROLO [2,1-B] [1,3]BENZOTHIAZEPINES | SIGMA TAU IND FARMACEUTI (IT) | 2004-03-17 | — | — | EP | disclosed |
| EP-1305318-A1 | PROCESS FOR THE PREPARATION OF 9-AMINO SUBSTITUTED 9,10-DIHYDROPYRROLO 2,1-B] 1,3]BENZOTIAZEPINES | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 2003-05-02 | — | — | EP | disclosed |