Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 7/20 | 0.42 |
| ▸ | HRH1 | P35367 | 3/20 | 0.41 |
| ▸ | HTR2C | P28335 | 3/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MTOR | P42345 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8169090 | 0.77 | DRD2 (0.48) | HTR2ADRD2HRH1HTR2CDRD4 | |
| SCHEMBL6783782 | 0.77 | ANPEP (0.47) | HTR2AANPEPMAPTALDH1A1 | |
| SCHEMBL20829222 | 0.77 | DRD2 (0.44) | HTR2ADRD2HRH1HTR2CDRD4 | |
| SCHEMBL22270141 | 0.77 | DRD2 (0.44) | HTR2ADRD2HRH1HTR2CDRD4 | |
| SCHEMBL9873313 | 0.77 | DRD2 (0.41) | HTR2ADRD2HRH1HTR2CDRD4 | |
| SCHEMBL6779110 | 0.77 | ANPEP (0.36) | HTR2ATP53CYP3A4CYP2D6ANPEP | |
| SCHEMBL2463276 | 0.77 | — | — | |
| SCHEMBL31373436 | 0.77 | — | — | |
| SCHEMBL31373438 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL19926846 | 0.74 | KDM1A (0.57) | HTR2AHRH1HTR2CANPEPKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5141960-A | Central nervous system disorders | G. D. SEARLE & CO. (US) | 1992-08-25 | — | — | US | disclosed |