Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 15/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6635678 | 0.95 | TRPV1 (0.41) | MAPK1TRPV1 | |
| SCHEMBL6685602 | 0.85 | ALDH1A1 (0.54) | ALDH1A1TSHRMEN1POLBKMT2A | |
| SCHEMBL6639886 | 0.83 | TSHR (0.44) | MAPK1ALDH1A1TSHRTRPV1MEN1 | |
| SCHEMBL6637965 | 0.82 | ALDH1A1 (0.47) | ALDH1A1TSHRMEN1POLBKMT2A | |
| SCHEMBL6637090 | 0.77 | TRPV1 (0.43) | MAPK1ALDH1A1TSHRTRPV1MEN1 | |
| SCHEMBL6636955 | 0.71 | ROCK2 (0.53) | — | |
| SCHEMBL6642854 | 0.68 | KDM4C (0.44) | — | |
| SCHEMBL6643917 | 0.67 | ROCK2 (0.43) | ALDH1A1 | |
| SCHEMBL6636985 | 0.67 | ALDH1A1 (0.64) | ALDH1A1TSHRMEN1POLBKMT2A | |
| SCHEMBL2319982 | 0.67 | TRPV1 (0.68) | ALDH1A1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0984967-B1 | NAPHTHYRIDINE DERIVATIVES AND THEIR ANALOGUES INHIBITING CYTOMEGALOVIRUS | IAF BIOCHEM INT (CA) | 2004-02-25 | — | — | EP | claimed |
| EP-1037633-B1 | ANTIVIRAL COMPOUNDS | IAF BIOCHEM INT (CA) | 2003-09-10 | — | — | EP | claimed |