⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6648064 | 0.82 | — | — | |
| SCHEMBL6646905 | 0.79 | ALDH1A1 (0.33) | — | |
| SCHEMBL6642803 | 0.72 | TSHR (0.37) | — | |
| SCHEMBL6622199 | 0.70 | MAOB (0.34) | — | |
| SCHEMBL6641995 | 0.70 | — | — | |
| SCHEMBL6642625 | 0.69 | GABRP (0.36) | — | |
| SCHEMBL6132657 | 0.69 | KDM4E (0.31) | — | |
| SCHEMBL7015156 | 0.68 | CYP3A4 (0.33) | — | |
| SCHEMBL3598196 | 0.67 | ALOX5AP (0.34) | — | |
| SCHEMBL6133199 | 0.66 | TTR (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807105-B1 | PYRIDOPYRIMIDONES, QUINOLINES AND FUSED N-HERETOCYCLES AS BRADYKININ ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-06-16 | — | — | EP | disclosed |
| US-5994368-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, ANALGESICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-30 | — | — | US | disclosed |
| WO-1996013485-A1 | PYRIDOPYRIMIDONES, QUINOLINES AND FUSED N-HERETOCYCLES AS BRADYKININ ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-09 | — | — | WO | disclosed |