Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 4/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL6634718 | 0.92 | PGR (0.38) | PGRBACE1HTR2ATGM2HDAC4 | |
| SCHEMBL6637300 | 0.80 | PDE7A (0.49) | PGRBACE1HTR2APDE7AHDAC4 | |
| Hydrochloric Acid SCHEMBL6642284 | 0.79 | PDE7A (0.48) | PGRBACE1HTR2APDE7AHDAC4 | |
| SCHEMBL6637532 | 0.77 | BACE1 (0.52) | PGRBACE1HTR2A | |
| Hydrochloric Acid SCHEMBL6639312 | 0.76 | BACE1 (0.51) | PGRBACE1HTR2A | |
| SCHEMBL6634247 | 0.71 | PGR (0.40) | PGRHTR2ATGM2 | |
| SCHEMBL7495240 | 0.71 | BACE1 (0.35) | BACE1HTR2A | |
| SCHEMBL7493750 | 0.71 | BACE1 (0.35) | BACE1HTR2A | |
| SCHEMBL6637994 | 0.71 | PGR (0.40) | PGRHTR2ATGM2 | |
| SCHEMBL6633957 | 0.71 | PGR (0.40) | PGRHTR2ATGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202994-B1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 2004-04-14 | — | — | EP | claimed |