Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 1/20 | 0.52 |
| ▸ | GNRHR | P30968 | 1/20 | 0.52 |
| ▸ | GPR183 | P32249 | 1/20 | 0.52 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.52 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6642036 | 0.89 | FPR1 (0.51) | FPR1GNRHRGPR183GPR119S1PR4 | |
| SCHEMBL6642600 | 0.89 | FPR1 (0.48) | FPR1GNRHRGPR183GPR119S1PR4 | |
| SCHEMBL6667891 | 0.87 | FPR1 (0.52) | FPR1GNRHRGPR183GPR119ALDH1A1 | |
| SCHEMBL6670600 | 0.86 | MAPT (0.50) | FPR1GNRHRGPR183GPR119ALDH1A1 | |
| SCHEMBL6679959 | 0.86 | ALDH1A1 (0.60) | FPR1GNRHRGPR183GPR119S1PR4 | |
| SCHEMBL6638649 | 0.86 | GNRHR (0.63) | FPR1GNRHRGPR183GPR119S1PR4 | |
| SCHEMBL6670469 | 0.86 | FPR1 (0.51) | FPR1GNRHRGPR183GPR119ALDH1A1 | |
| SCHEMBL6642691 | 0.86 | FPR1 (0.48) | FPR1GNRHRGPR183GPR119S1PR4 | |
| SCHEMBL6666570 | 0.85 | FPR1 (0.55) | FPR1GNRHRGPR183GPR119S1PR4 | |
| SCHEMBL4858943 | 0.85 | FPR1 (0.46) | FPR1GNRHRGPR183GPR119S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401427-A4 | NON-PEPTIDE GNRH AGENTS, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THEIR USES, AND PROCESSES FOR PREPARING THEM | AGOURON PHARMA (US) | 2004-12-01 | — | — | EP | disclosed |
| EP-1401427-A2 | NON-PEPTIDE GNRH AGENTS, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THEIR USES, AND PROCESSES FOR PREPARING THEM | Agouron Pharmaceuticals, Inc. (US) | 2004-03-31 | — | — | EP | disclosed |
| WO-2002098363-A2 | NON-PEPTIDE GnRH AGENTS, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THEIR USES, AND PROCESSES FOR PREPARING THEM | AGOURON PHARMACEUTICALS, INC. (US) | 2002-12-12 | — | — | WO | disclosed |