Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.74 |
| ▸ | PLG | P00747 | 1/20 | 0.70 |
| ▸ | PROC | P04070 | 1/20 | 0.70 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.65 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14509265 | 0.82 | F10 (1.00) | F10PLGPROCPRSS1F2 | |
| Trifluoroacetic Acid SCHEMBL6641128 | 0.81 | F10 (0.67) | F10PLGPROCPRSS1F2 | |
| SCHEMBL13636885 | 0.77 | F10 (0.76) | F10PLGPROCPRSS1F2 | |
| Trifluoroacetic Acid SCHEMBL7897485 | 0.76 | F10 (0.70) | F10PLGPROCPRSS1F2 | |
| Trifluoroacetic Acid SCHEMBL6644219 | 0.75 | F10 (0.88) | F10PLGPROCPRSS1ITGB3 | |
| Trifluoroacetic Acid SCHEMBL6664969 | 0.75 | F10 (0.88) | F10PLGPROCPRSS1F2 | |
| Trifluoroacetic Acid SCHEMBL6638539 | 0.74 | F10 (0.68) | F10PLGPROCPRSS1F2 | |
| SCHEMBL7898536 | 0.74 | F10 (0.57) | F10PLGPRSS1F2 | |
| SCHEMBL6639955 | 0.74 | F10 (0.57) | F10PLGPRSS1F2 | |
| Trifluoroacetic Acid SCHEMBL6638375 | 0.73 | F10 (0.88) | F10PLGPROCPRSS1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0931060-B1 | SUBSTITUTED N- (AMINOIMINOMETHYL OR AMINOMETHYL)PHENYL PROPYL AMIDES | AVENTIS PHARMA INC (US) | 2009-11-25 | — | — | EP | disclosed |