Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ABL2 | P42684 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.33 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.33 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.33 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.33 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.33 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6643338 | 1.00 | BAZ2B (0.36) | BAZ2BMAPK1GAAFBP1ABL1 | |
| SCHEMBL6644322 | 0.87 | KDM4E (0.39) | MAPK1GAAFBP1ABL1EGFR | |
| SCHEMBL6644319 | 0.87 | KDM4E (0.39) | MAPK1GAAFBP1ABL1EGFR | |
| SCHEMBL6641840 | 0.86 | MTNR1A (0.37) | BAZ2BMAPK1GAAFBP1ABL1 | |
| SCHEMBL6641843 | 0.86 | MTNR1A (0.37) | BAZ2BMAPK1GAAFBP1ABL1 | |
| SCHEMBL6643618 | 0.84 | HTR6 (0.44) | MAPK1GAAKMT2AALDH1A1HTR2C | |
| SCHEMBL6643619 | 0.84 | HTR6 (0.44) | MAPK1GAAKMT2AALDH1A1HTR2C | |
| SCHEMBL6641924 | 0.84 | GAA (0.34) | MAPK1GAAFBP1ABL1EGFR | |
| SCHEMBL6641928 | 0.84 | GAA (0.34) | MAPK1GAAFBP1ABL1EGFR | |
| SCHEMBL27483846 | 0.83 | MAPK1 (0.33) | MAPK1GAAMEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1165537-C | Pyrroloindoles, pyridoindoles and aza * -indoles as 5-HT 2C agonists | О | 2004-09-08 | — | — | CN | disclosed |
| EP-1109813-B1 | PYRROLOINDOLES, PYRIDOINDOLES AND AZEPINOINDOLES AS 5-HT2C AGONISTS | VERNALIS RES LTD (GB) | 2004-08-11 | — | — | EP | disclosed |
| US-6433175-B1 | ANTISEROTONINE AGENTS | VERNALIS RESEARCH LIMITED (GB) | 2002-08-13 | — | — | US | disclosed |
| CN-1325399-A | Pyrroloindoles, pyridoindoles and azaindoles as 5-HT 2C agonists | CEREBRUS RES LTD (GB) | 2001-12-05 | — | — | CN | disclosed |