Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.49 |
| ▸ | LDHB | P07195 | 1/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ASPH | Q12797 | 1/20 | 0.41 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.41 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.37 |
| ▸ | VNN1 | O95497 | 1/20 | 0.37 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.37 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.37 |
| ▸ | LIPC | P11150 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5881730 | 0.85 | PTGER4 (0.48) | LDHALDHBPDE10APTGER4KDM4E | |
| SCHEMBL26914521 | 0.84 | HCAR3 (0.53) | LDHALDHBKDM4EHCAR3 | |
| SCHEMBL26914522 | 0.84 | HCAR3 (0.53) | LDHALDHBKDM4EHCAR3 | |
| SCHEMBL5881801 | 0.79 | PRKCQ (0.47) | HCAR3 | |
| SCHEMBL3367671 | 0.76 | PTGER4 (0.41) | LDHALDHBPDE10APTGER4FFAR2 | |
| SCHEMBL16076739 | 0.75 | VNN1 (0.49) | LDHALDHBPDE10AKDM4CKDM4E | |
| SCHEMBL16049359 | 0.74 | VNN1 (0.48) | LDHALDHBPDE10AKDM4CKDM4E | |
| SCHEMBL15774700 | 0.74 | PTGER4 (0.67) | LDHALDHBPTGER4KDM4CKDM4E | |
| SCHEMBL6644250 | 0.73 | PRKCQ (0.46) | PIM1 | |
| SCHEMBL19172463 | 0.72 | CNR1 (0.39) | KDM4EHCAR3FFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1390350-A1 | NOVEL COMPOUNDS | AstraZeneca AB (SE) | 2004-02-25 | — | — | EP | disclosed |
| WO-2002085866-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2002-10-31 | — | — | WO | disclosed |