Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 5/20 | 0.61 |
| ▸ | ALDH3A1 | P30838 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6170599 | 0.90 | HTT (0.61) | HTTALDH3A1L3MBTL1POLBNOD1 | |
| SCHEMBL19848205 | 0.80 | HTT (0.69) | HTTALDH3A1L3MBTL1POLBNOD1 | |
| SCHEMBL15999986 | 0.78 | PPARG (0.71) | HTTALDH3A1L3MBTL1POLBNOD1 | |
| SCHEMBL11607293 | 0.78 | HTT (0.70) | HTTALDH3A1L3MBTL1POLBNOD1 | |
| SCHEMBL6169770 | 0.77 | SMN1; SMN2 (0.74) | HTTALDH3A1L3MBTL1POLBNOD1 | |
| SCHEMBL8329551 | 0.76 | ALDH3A1 (1.00) | HTTALDH3A1L3MBTL1POLBNOD1 | |
| SCHEMBL1780727 | 0.76 | RAPGEF4 (0.74) | HTTL3MBTL1POLBHPGDLMNA | |
| SCHEMBL1553465 | 0.75 | PDE4A (0.62) | L3MBTL1ALDH1A1SMN1; SMN2RAPGEF4 | |
| Hydrochloric Acid SCHEMBL8601366 | 0.74 | PDE4A (0.61) | L3MBTL1ALDH1A1SMN1; SMN2RAPGEF4 | |
| SCHEMBL8652798 | 0.74 | CPT1A (0.63) | HTTHPGDLMNAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986384-A4 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIV PITTSBURGH (US) | 2004-09-15 | — | — | EP | disclosed |
| US-6310095-B1 | INHIBITING OR TREATING CANCER, TREATING INTIMAL HYPERPLASIA ASSOCIATED WITH RESTENOSIS AND ATHEROSCLEROSIS, INHIBITING POST-TRANSLATIONAL MODIFICATION OF ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE AND/OR GERANYLGERANYLTRANSFERASE | UNIVERSITY OF PITTSBURGH | 2001-10-30 | — | — | US | disclosed |
| EP-0986384-A1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 2000-03-22 | — | — | EP | disclosed |
| WO-1998050029-A1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1998-11-12 | — | — | WO | disclosed |