Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 8/20 | 0.63 |
| ▸ | NQO2 | P16083 | 8/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6645774 | 1.00 | PPARD (0.63) | PPARDNQO2MTNR1AMTNR1BPPARA | |
| SCHEMBL4624248 | 0.93 | SIGMAR1 (0.59) | — | |
| SCHEMBL1980554 | 0.89 | PPARD (0.56) | PPARDNQO2MTNR1AMTNR1B | |
| SCHEMBL4622325 | 0.85 | SIGMAR1 (0.56) | PPARD | |
| SCHEMBL4623118 | 0.84 | CYP24A1 (0.63) | PPARD | |
| SCHEMBL2995086 | 0.84 | PPARD (0.80) | PPARDPPARA | |
| SCHEMBL820621 | 0.84 | PPARD (0.80) | PPARDPPARA | |
| SCHEMBL821101 | 0.84 | PPARD (0.80) | PPARDPPARA | |
| SCHEMBL8434825 | 0.81 | CYP19A1 (0.60) | PPARDNQO2MTNR1AMTNR1B | |
| SCHEMBL7166421 | 0.81 | CYP24A1 (0.61) | PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1414809-A1 | INDANE ACETIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICAL AGENTS, INTERMEDIATES, AND METHOD OF PREPARATION | Bayer Corporation (US) | 2004-05-06 | — | — | EP | disclosed |
| WO-2003011842-A1 | INDANE ACETIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICAL AGENTS, INTERMEDIATES, AND METHOD OF PREPARATION | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-02-13 | — | — | WO | disclosed |