Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.60 |
| ▸ | CYP24A1 | Q07973 | 4/20 | 0.51 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.51 |
| ▸ | CYP27A1 | Q02318 | 2/20 | 0.48 |
| ▸ | METAP1 | P53582 | 1/20 | 0.47 |
| ▸ | NQO2 | P16083 | 8/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4623118 | 0.91 | CYP24A1 (0.63) | CYP19A1CYP24A1CYP26A1CYP27A1METAP1 | |
| SCHEMBL7166421 | 0.87 | CYP24A1 (0.61) | CYP19A1CYP24A1CYP26A1CYP27A1METAP1 | |
| SCHEMBL7295884 | 0.85 | CYP19A1 (0.65) | CYP19A1CYP24A1CYP26A1CYP27A1METAP1 | |
| SCHEMBL8028175 | 0.85 | CYP19A1 (0.61) | CYP19A1CYP24A1CYP26A1CYP27A1METAP1 | |
| SCHEMBL7228543 | 0.84 | CYP19A1 (0.53) | CYP19A1CYP24A1CYP26A1NQO2MTNR1A | |
| SCHEMBL4621209 | 0.83 | CYP24A1 (0.65) | CYP19A1CYP24A1CYP26A1CYP27A1METAP1 | |
| SCHEMBL6645779 | 0.81 | PPARD (0.63) | NQO2MTNR1AMTNR1BPPARD | |
| SCHEMBL6645774 | 0.81 | PPARD (0.63) | NQO2MTNR1AMTNR1BPPARD | |
| SCHEMBL27599825 | 0.80 | ACHE (0.46) | NQO2MTNR1AMTNR1B | |
| SCHEMBL7302984 | 0.79 | CYP19A1 (0.60) | CYP19A1CYP24A1CYP26A1CYP27A1METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945561-A | ANTIINFLAMMATORY AGENT, RHEUMATIC DISORDERS, SKIN DISORDERS,ANTISCARRING AGENT | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-08-31 | — | — | US | disclosed |
| WO-1998049136-A1 | RETINOID-LIKE COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |