Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 9/20 | 1.00 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.63 |
| ▸ | HTR3B | O95264 | 3/20 | 0.63 |
| ▸ | HTR3A | P46098 | 3/20 | 0.63 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.63 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.63 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.63 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.57 |
| ▸ | NCF1 | P14598 | 1/20 | 0.57 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.57 |
| ▸ | LTA4H | P09960 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.53 |
| ▸ | HTR6 | P50406 | 2/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | HTR1D | P28221 | 1/20 | 0.53 |
| ▸ | HTR1B | P28222 | 1/20 | 0.53 |
| ▸ | HTR7 | P34969 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL81940 | 1.00 | ADRB1 (1.00) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| Hydrochloric Acid SCHEMBL314404 | 0.98 | ADRB1 (0.96) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| Hydrochloric Acid SCHEMBL3719334 | 0.98 | ADRB1 (0.96) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| Water SCHEMBL27430691 | 0.96 | ADRB1 (0.92) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| Dimethylamine SCHEMBL28750709 | 0.94 | ADRB1 (0.88) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL82301 | 0.92 | ADRB1 (0.85) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| Bicarbonate SCHEMBL11620170 | 0.90 | ADRB1 (0.81) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL21548392 | 0.89 | ADRB1 (0.79) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL7136974 | 0.89 | ADRB1 (0.79) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL2881718 | 0.89 | ADRB1 (0.79) | ADRB1HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040249147-A1 | Synthesis of key azole-antifungal intermediates | RANBAXY LABORATORIES LIMITED (IN) | 2004-12-09 | — | — | US | disclosed |
| EP-1432704-A1 | SYNTHESIS OF KEY AZOLE-ANTIFUNGAL INTERMEDIATES | RANBAXY LABORATORIES, LTD. (IN) | 2004-06-30 | — | — | EP | disclosed |
| WO-2003027103-A1 | SYNTHESIS OF KEY AZOLE-ANTIFUNGAL INTERMEDIATES | RANBAXY LABORATORIES LIMITED (IN) | 2003-04-03 | — | — | WO | disclosed |
| EP-0454501-B1 | Benzylidenethiazolidine derivatives, their preparation and their use for the inhibition of lipid peroxides | SANKYO CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| EP-0839812-A1 | Preparation of benzylthiazolidine derivatives | Sankyo Company Limited (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5387596-A | Treating arteriosclerosis | SANKYO COMPANY, LIMITED (JP) | 1995-02-07 | — | — | US | disclosed |
| EP-0454501-A2 | Benzylidenethiazolidine derivatives, their preparation and their use for the inhibition of lipid peroxides | Sankyo Company Limited (JP) | 1991-10-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040249147-A1 | Synthesis of key azole-antifungal intermediates | ERG28, CYP11B1, CYP2E1 | ADRB1 2635/4885HTR3E 3924/4885HTR3B 2857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.