Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.46 |
| ▸ | UBA2 | Q9UBT2 | 2/20 | 0.46 |
| ▸ | CDC25B | P30305 | 2/20 | 0.46 |
| ▸ | UBE2I | P63279 | 1/20 | 0.46 |
| ▸ | TYMS | P04818 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 2/20 | 0.42 |
| ▸ | DDO | Q99489 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6647787 | 0.85 | LMNA (0.53) | SAE1UBA2CDC25BUBE2IDAO | |
| SCHEMBL824649 | 0.81 | KDM4E (0.63) | SAE1UBA2CDC25BUBE2ITYMS | |
| SCHEMBL6644990 | 0.78 | PIM1 (0.43) | CDC25BTYMSGAALMNATUBB4A | |
| SCHEMBL1719929 | 0.78 | TYMS (0.50) | SAE1UBA2CDC25BUBE2ITYMS | |
| SCHEMBL14867343 | 0.75 | HPGD (0.57) | SAE1UBA2CDC25BUBE2IKDM4E | |
| SCHEMBL29784203 | 0.75 | KDM4E (0.60) | SAE1UBA2CDC25BUBE2IKDM4E | |
| SCHEMBL150458 | 0.75 | KDM4E (0.60) | SAE1UBA2CDC25BUBE2IKDM4E | |
| SCHEMBL6645110 | 0.73 | PARP1 (0.49) | SAE1UBA2CDC25BUBE2ITYMS | |
| SCHEMBL28629567 | 0.73 | KDM4E (0.59) | SAE1UBA2CDC25BUBE2IKDM4E | |
| SCHEMBL30160749 | 0.73 | KDM4E (0.59) | SAE1UBA2CDC25BUBE2IKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040176361-A1 | Fused heterocyclic compound and medicinal use thereof | MITSUBISHI PHARMA CORPORATION (JP) | 2004-09-09 | — | — | US | disclosed |
| EP-1396488-A1 | FUSED HETEROCYCLIC COMPOUND AND MEDICINAL USE THEREOF | Mitsubishi Pharma Corporation (JP) | 2004-03-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176361-A1 | Fused heterocyclic compound and medicinal use thereof | PARP11, PARP1, CD38 | SAE1 509/4885UBA2 2502/4885CDC25B 3854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.