⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6647135 | 0.74 | CHRNB2 (0.38) | — | |
| SCHEMBL142200 | 0.72 | — | — | |
| SCHEMBL4723234 | 0.67 | TFPI2 (0.32) | — | |
| SCHEMBL1468528 | 0.62 | — | — | |
| SCHEMBL27482403 | 0.61 | SIGMAR1 (0.41) | — | |
| SCHEMBL5561904 | 0.61 | — | — | |
| Hydrochloric Acid SCHEMBL4365776 | 0.60 | — | — | |
| SCHEMBL15750131 | 0.60 | SIGMAR1 (0.39) | — | |
| SCHEMBL4214811 | 0.59 | — | — | |
| SCHEMBL22032719 | 0.59 | TFPI2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106946887-A | It is a kind of to introduce the new technology that catalyst optimization synthesizes Dipyridamole | 大连万福制药有限公司 | 2017-07-14 | — | — | CN | claimed |
| WO-2021043217-A1 | COMPOUND HAVING AXL AND C-MET KINASE INHIBITORY ACTIVITY, PREPARATION THEREOF AND APPLICATION THEREOF | 中国科学院上海药物研究所 | 2021-03-11 | — | — | WO | disclosed |
| CN-106983751-A | Two ring substituted uracils and application thereof | 拜耳医药股份有限公司 | 2017-07-28 | — | — | CN | disclosed |
| CN-106946887-A | It is a kind of to introduce the new technology that catalyst optimization synthesizes Dipyridamole | 大连万福制药有限公司 | 2017-07-14 | — | — | CN | disclosed |
| CN-104395310-B | Bicyclic substituted uracils and their use | 拜耳药业股份公司 | 2017-05-03 | — | — | CN | disclosed |
| CN-104395310-A | Bicyclic substituted uracils and their use | Bayer Pharma AG | 2015-03-04 | — | — | CN | disclosed |
| EP-1299362-A4 | SELECTIVE MELANIN CONCENTRATING HORMONE-1 (MCH1) RECEPTOR ANTAGONISTS AND USES THEREOF | SYNAPTIC PHARMA CORP (US) | 2004-11-03 | — | — | EP | disclosed |
| EP-1299362-A1 | SELECTIVE MELANIN CONCENTRATING HORMONE-1 (MCH1) RECEPTOR ANTAGONISTS AND USES THEREOF | Synaptic Pharmaceutical Corporation (US) | 2003-04-09 | — | — | EP | disclosed |
| WO-2002006245-A1 | SELECTIVE MELANIN CONCENTRATING HORMONE-1 (MCH1) RECEPTOR ANTAGONISTS AND USES THEREOF | SYNAPTIC PHARMARCEUTICAL CORPORATION (US) | 2002-01-24 | — | — | WO | disclosed |