⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6827448 | 0.75 | — | — | |
| Dichloroacetic Acid SCHEMBL28391863 | 0.70 | — | — | |
| SCHEMBL985627 | 0.67 | — | — | |
| SCHEMBL186056 | 0.67 | — | — | |
| SCHEMBL487015 | 0.67 | — | — | |
| Dichloroacetic Acid SCHEMBL7777 | 0.67 | — | — | |
| Dichloroacetic Acid SCHEMBL5307050 | 0.67 | LMNA (1.00) | — | |
| Dichloroacetic Acid SCHEMBL1331776 | 0.67 | — | — | |
| SCHEMBL1331263 | 0.67 | — | — | |
| SCHEMBL1332066 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392655-A2 | POTASSIUM CHANNEL OPENERS | Abbott Laboratories (US) | 2004-03-03 | — | — | EP | disclosed |
| EP-1358160-A1 | AMINAL DIONES AS POTASSIUM CHANNEL OPENERS | Abbott Laboratories (US) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002062762-A2 | POTASSIUM CHANNEL OPENERS | ABBOTT LABORATORIES (US) | 2002-08-15 | — | — | WO | disclosed |
| WO-2002062761-A1 | AMINAL DIONES AS POTASSIUM CHANNEL OPENERS | ABBOTT LABORATORIES (US) | 2002-08-15 | — | — | WO | disclosed |
| US-5684127-A | SELECTIVELY PROTECTING AMINO GROUPS AND PHENOLIC HYDROXY GROUPS OF A PENTAPEPTIDE, OXIDIZING THE HYDROXYMETHYL MOIETY OF PROTECTED PENTAPEPTIDE TO CARBOXY, DEPROTECTING AMINO GROUP AND SUBMITTING COMPOUND TO DEGRADATION | GRUPPO LEPETIT SPA (IT) | 1997-11-04 | — | — | US | disclosed |
| US-5644025-A | AGLYCON DALBAHEPTIDE ANTIBIOTICS FOR CYCLIC TETRAPEPTIDES FOR BACTERICIDES | GRUPPO LEPETIT SPA (IT) | 1997-07-01 | — | — | US | disclosed |
| EP-0282895-B1 | 2-oxa-isocephem compounds, compositions containing same and processes for preparing same | OTSUKA PHARMA CO LTD (JP) | 1995-06-07 | — | — | EP | disclosed |
| EP-0561827-B1 | TETRAPEPTIDES DERIVING FROM DALBAHEPTIDE ANTIBIOTICS | LEPETIT SPA (IT) | 1995-04-12 | — | — | EP | disclosed |
| EP-0561827-A1 | TETRAPEPTIDES DERIVING FROM DALBAHEPTIDE ANTIBIOTICS. | LEPETIT SPA (IT) | 1993-09-29 | — | — | EP | disclosed |
| WO-1992010517-A1 | TETRAPEPTIDES DERIVING FROM DALBAHEPTIDE ANTIBIOTICS | GRUPPO LEPETIT S.P.A. (IT) | 1992-06-25 | — | — | WO | disclosed |
| US-5037976-A | Antimicrobial Agent | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-08-06 | — | — | US | disclosed |
| US-4898859-A | 2-Oxa-isocephem compounds and compositions containing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-06 | — | — | US | disclosed |
| EP-0282895-A2 | 2-oxa-isocephem compounds, compositions containing same and processes for preparing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-09-21 | — | — | EP | disclosed |